Heart Function in Patients Assessed for Sleep Apnoea

NCT ID: NCT03226652

Last Updated: 2021-02-17

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

101 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-24

Study Completion Date

2019-04-01

Brief Summary

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This study aims to determine the prevalence and prognosis of heart failure with preserved ejection function (HFpEF) among patients being assessed for sleep disordered breathing (SDB).

Detailed Description

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Patients with sleep disordered breathing (SDB) and those with heart failure with preserved ejection fraction (HFpEF) share similar characteristics. Increasing age, hypertension, obesity, diabetes mellitus and atrial fibrillation are well recognised links in both groups. It also known that SDB is common in patients with heart failure, both with reduced and preserved ejection fraction. It is therefore hypothesised that among patients being referred for SDB assessment, we can identify a group with unrecognised HFpEF.

Conditions

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Heart Failure With Preserved Ejection Fraction Sleep Disordered Breathing Heart Failure With Normal Ejection Fraction Obstructive Sleep Apnea Central Sleep Apnea Heart Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with clinically suspected sleep disordered breathing (SDB)

Patients referred for Sleep disordered breathing assessment.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Aged ≥40 years and referred for respiratory polygraphy

Exclusion Criteria

* Previous diagnosis of Heart Failure
* Treated sleep disordered breathing
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Royal Brompton & Harefield NHS Foundation Trust

OTHER

Sponsor Role collaborator

Imperial College London

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Martin R Cowie, MD MSc

Role: PRINCIPAL_INVESTIGATOR

Imperial College London

Locations

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Royal Brompton Hospital

London, , United Kingdom

Site Status

Countries

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United Kingdom

Provided Documents

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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

View Document

Other Identifiers

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17IC3980

Identifier Type: -

Identifier Source: org_study_id

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