A Real World Evaluation of the ELUVIA Stent in Subjects With Lesions Located in the Femoropopliteal Arteries

NCT ID: NCT03037411

Last Updated: 2022-11-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

291 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-12-13

Study Completion Date

2022-03-24

Brief Summary

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The REGAL study is a European, prospective, multi-center Post-Market Clinical Follow-up (PMCF) trial providing additional data including health economics data to support the use of the ELUVIA stent in the treatment of lesions located in the femoropopliteal arteries.

Detailed Description

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A European, prospective, multi-center Post-Market Clinical Follow-up (PMCF) trial providing additional data including health economics data to support the use of the ELUVIA stent in the treatment of lesions located in the femoropopliteal arteries.

The objective of the study is to collect additional data including health economics data to support the use of the ELUVIA Drug-Eluting Vascular Stent System (ELUVIA Stent) for treating Superficial Femoral Artery (SFA) and/or Proximal Popliteal Artery (PPA) lesions.

Conditions

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Arterial Occlusive Diseases Atherosclerosis Vascular Diseases Arteriosclerosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ELUVIA stent implantation

Peripheral stenting

Peripheral stenting

Intervention Type DEVICE

stent implantation during the index procedure

Interventions

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Peripheral stenting

stent implantation during the index procedure

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Subjects age 18 and older
2. Subject is willing and able to provide written consent before any study-specific test or procedure is performed and agrees to attend all follow-up visits
3. De novo, restenotic or (re)occluded lesions in the native femoro-popliteal arteries, with reference vessel diameter (RVD) ranging from 4.0-6.0 mm, suitable for endovascular treatment

Exclusion Criteria

1. Subject is pregnant or planning to become pregnant during the course of the study
2. Life expectancy of less than 1 year (which is defined as documented life expectancy less than 12 months due to other medical co-morbid condition(s) that could limit the subject's ability to participate in the clinical follow-up, limit the subject's compliance with the standard of care follow-up, or impact the scientific integrity of the trial)
3. Known allergy to the ELUVIA stent system or any of its components, concomitant medication, contrast agents (that cannot be medically managed)
4. Subject enrolled in an investigational study that has not reached primary endpoint at the time of enrollment or that clinically interferes with the current study assessments (Note: studies requiring extended follow-up for products that were investigational, but have become commercially available since then are not considered investigational studies)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boston Scientific Corporation

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Carlo Setacci

Role: PRINCIPAL_INVESTIGATOR

Policlinico Le Scotte, Siena

Locations

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Medizinische Universität Graz

Graz, , Austria

Site Status

ZOL Genk

Genk, Limburg, Belgium

Site Status

Regionaal Ziekenhuis Heilig Hart Tienen

Tienen, Vlaams-Brabant, Belgium

Site Status

CHU Sart Tilman

Liège, , Belgium

Site Status

Centre Hospitalier Universitaire Grenoble-Alpes

Grenoble, , France

Site Status

Clinique Parly II

Le Chesnay, , France

Site Status

ASL Asti

Asti, , Italy

Site Status

Policlinico Vittorio Emanuele

Catania, , Italy

Site Status

Policlinico di Monza

Monza, , Italy

Site Status

Policlinico Umberto I

Roma, , Italy

Site Status

L'Azienda sanitaira ASL Roma 1

Roma, , Italy

Site Status

IRCCS Policlinico San Donato

San Donato Milanese, , Italy

Site Status

Hospital Azienda Ospedaliera Universitaria Senese

Siena, , Italy

Site Status

Hospital Universitario de Burgos

Burgos, , Spain

Site Status

Hosp. Puerta del Mar

Cadiz, , Spain

Site Status

Hospital San Pedro de Alcántara

Cáceres, , Spain

Site Status

Hosp . Universitario de Guadalajara

Guadalajara, , Spain

Site Status

Hosp. Ntra Sra. del Rosario

Madrid, , Spain

Site Status

Hospital Clinico San Carlos

Madrid, , Spain

Site Status

Hosp. Complejo Hosp Universitario (CHUO)

Ourense, , Spain

Site Status

Hospital de Montecelo (Pontevedra EOXI)

Pontevedra, , Spain

Site Status

Hospital Parc Tauli

Sabadell, , Spain

Site Status

Foundation for the Aragonese Healthcare Research Institute

Zaragoza, , Spain

Site Status

Countries

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Austria Belgium France Italy Spain

Other Identifiers

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S2346

Identifier Type: -

Identifier Source: org_study_id

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