Brief Treatment for Posttraumatic Stress Disorder

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

169 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-20

Study Completion Date

2021-03-31

Brief Summary

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The primary goal of this study is to examine whether a brief treatment approach for PTSD is equally efficacious in the treatment of active duty service members relative to a first line treatment approach that requires much greater treatment dose.

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Detailed Description

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The goal of this randomized clinical trial is to investigate if a brief, written intervention for posttraumatic stress disorder (PTSD), Written Exposure Therapy (WET), is non-inferior compared to an evidenced-based behavioral therapy, Cognitive Processing Therapy-Cognition only (CPT-C), in the treatment of PTSD in active duty military men and women with a diagnosis of PTSD who have deployed in support of a post-9/11. The primary study outcome is change in symptom severity as assessed by the Clinician Administered PTSD Scale for Diagnostic and Statistical Manual-5 edition (CAPS-5). Independent assessors evaluated participants using the CAPS-5 at baseline, 10-, 20-, and 30-week after the first treatment session.

Conditions

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PTSD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Written exposure therapy

5 sessions of imaginal exposure therapy.

Group Type EXPERIMENTAL

written exposure therapy

Intervention Type BEHAVIORAL

five sessions of writing about traumatic experience.

CPT, cognitive only

12 sessions of cognitive therapy.

Group Type ACTIVE_COMPARATOR

CPT, cognitive only

Intervention Type BEHAVIORAL

12 sessions of cognitive therapy related to traumatic experience.

Interventions

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written exposure therapy

five sessions of writing about traumatic experience.

Intervention Type BEHAVIORAL

CPT, cognitive only

12 sessions of cognitive therapy related to traumatic experience.

Intervention Type BEHAVIORAL

Other Intervention Names

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WET CPT-C

Eligibility Criteria

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Inclusion Criteria

* Male and female active duty military personnel who have deployed in support of a post-9/11 conflict seeking treatment for PTSD
* Diagnosis of PTSD
* Ability to speak, read and write English
* Not currently engaged in psychosocial treatment for PTSD
* Individuals taking psychotropic medications agree to work with their prescriber to remain on stable doses of any prescribed psychotropic medications for the duration of the intervention and through the first follow-up assessment as much as possible and as medically indicated.