Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ENROLLING_BY_INVITATION
NA
300 participants
INTERVENTIONAL
2020-01-22
2025-08-31
Brief Summary
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Detailed Description
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Specific Aim 1:To replicate previous findings supporting the efficacy of BCBT for the prevention of suicide attempts among military personnel and veterans (regardless of Axis I or II diagnosis). The standard null hypothesis will involve tests conducted comparing improvement following BCBT to Present-Centered Therapy (PCT)
Specific Aim 2: To identify cognitive-affective mediators of BCBT's effects on risk for suicide attempt.
Conditions
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Keywords
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Brief Cognitive Behavioral Therapy
Brief Cognitive Behavioral Therapy (BCBT)
Participants in BCBT receive 12 outpatient individual psychotherapy sessions scheduled on a weekly or biweekly basis, with the first session lasting 90 minutes and subsequent sessions lasting 60 minutes. BCBT was is delivered in three sequential phases. In phase I (5 sessions), the therapist identifies patient-specific factors that contribute to and maintain suicidal behaviors, provides a cognitive-behavioral conceptualization, collaboratively develops a crisis response plan, and teaches basic emotion regulation skills. In phase II (5 sessions), the therapist applies cognitive strategies to reduce beliefs and assumptions that serve as vulnerabilities to suicidal behavior. In phase III (2 sessions), a relapse prevention task is conducted.
Treatment as Usual (TAU)
All participants will receive the following interventions or procedures, regardless of treatment assignment:
* Suicide risk assessment using the Columbia Suicide Severity Rating Scale
* VA's safety planning intervention, which include Military Crisis Line contact information and lethal means access reduction
* Caring contacts and outreach
* Psychotropic medication, group therapy, substance abuse counseling, and other mental health interventions provided routinely as a part of treatment as usual
Present-Centered Therapy
Present-Centered Therapy (PCT)
Participants in PCT will receive will include 12 outpatient individual psychotherapy sessions scheduled on a weekly or biweekly basis, with the first session lasting 90 minutes and subsequent sessions lasting 60 minutes. PCT consists of (1) psychoeducation about the typical symptoms and features associated with suicidal thoughts and behaviors among military personnel; (2) normalization of symptoms; (3) experience of receipt of support and feedback from a licensed professional; and (4) positive interpersonal interactions.
Treatment as Usual (TAU)
All participants will receive the following interventions or procedures, regardless of treatment assignment:
* Suicide risk assessment using the Columbia Suicide Severity Rating Scale
* VA's safety planning intervention, which include Military Crisis Line contact information and lethal means access reduction
* Caring contacts and outreach
* Psychotropic medication, group therapy, substance abuse counseling, and other mental health interventions provided routinely as a part of treatment as usual
Interventions
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Brief Cognitive Behavioral Therapy (BCBT)
Participants in BCBT receive 12 outpatient individual psychotherapy sessions scheduled on a weekly or biweekly basis, with the first session lasting 90 minutes and subsequent sessions lasting 60 minutes. BCBT was is delivered in three sequential phases. In phase I (5 sessions), the therapist identifies patient-specific factors that contribute to and maintain suicidal behaviors, provides a cognitive-behavioral conceptualization, collaboratively develops a crisis response plan, and teaches basic emotion regulation skills. In phase II (5 sessions), the therapist applies cognitive strategies to reduce beliefs and assumptions that serve as vulnerabilities to suicidal behavior. In phase III (2 sessions), a relapse prevention task is conducted.
Present-Centered Therapy (PCT)
Participants in PCT will receive will include 12 outpatient individual psychotherapy sessions scheduled on a weekly or biweekly basis, with the first session lasting 90 minutes and subsequent sessions lasting 60 minutes. PCT consists of (1) psychoeducation about the typical symptoms and features associated with suicidal thoughts and behaviors among military personnel; (2) normalization of symptoms; (3) experience of receipt of support and feedback from a licensed professional; and (4) positive interpersonal interactions.
Treatment as Usual (TAU)
All participants will receive the following interventions or procedures, regardless of treatment assignment:
* Suicide risk assessment using the Columbia Suicide Severity Rating Scale
* VA's safety planning intervention, which include Military Crisis Line contact information and lethal means access reduction
* Caring contacts and outreach
* Psychotropic medication, group therapy, substance abuse counseling, and other mental health interventions provided routinely as a part of treatment as usual
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* 18 years of age or older
* Reporting current suicide ideation with intent to die and/or a suicide attempt within the past two weeks
* Ability to understand and speak the English language; and ability to complete the informed consent process.
Exclusion Criteria
18 Years
ALL
No
Sponsors
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United States Department of Defense
FED
Ohio State University
OTHER
Lowcountry Center for Veterans Research
UNKNOWN
Medical University of South Carolina
OTHER
University of Utah
OTHER
Responsible Party
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Craig Bryan
Professor
Principal Investigators
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Craig J Bryan, PsyD, ABPP
Role: PRINCIPAL_INVESTIGATOR
Ohio State University
Locations
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Naval Medical Center Camp Lejeune
Jacksonville, North Carolina, United States
The Ohio State University
Columbus, Ohio, United States
Lowcountry Center for Veterans Research
Charleston, South Carolina, United States
Countries
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References
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Bryan CJ, Rudd MD, Wertenberger E. Reasons for suicide attempts in a clinical sample of active duty soldiers. J Affect Disord. 2013 Jan 10;144(1-2):148-52. doi: 10.1016/j.jad.2012.06.030. Epub 2012 Aug 1.
Bryan CJ, Rudd MD. Life stressors, emotional distress, and trauma-related thoughts occurring in the 24 h preceding active duty U.S. soldiers' suicide attempts. J Psychiatr Res. 2012 Jul;46(7):843-8. doi: 10.1016/j.jpsychires.2012.03.012. Epub 2012 Apr 1.
Rudd MD, Bryan CJ, Wertenberger EG, Peterson AL, Young-McCaughan S, Mintz J, Williams SR, Arne KA, Breitbach J, Delano K, Wilkinson E, Bruce TO. Brief cognitive-behavioral therapy effects on post-treatment suicide attempts in a military sample: results of a randomized clinical trial with 2-year follow-up. Am J Psychiatry. 2015 May;172(5):441-9. doi: 10.1176/appi.ajp.2014.14070843. Epub 2015 Feb 13.
Bryan CJ, Mintz J, Clemans TA, Leeson B, Burch TS, Williams SR, Maney E, Rudd MD. Effect of crisis response planning vs. contracts for safety on suicide risk in U.S. Army Soldiers: A randomized clinical trial. J Affect Disord. 2017 Apr 1;212:64-72. doi: 10.1016/j.jad.2017.01.028. Epub 2017 Jan 23.
Bryan CJ, Khazem LR, Baker JC, Brown LA, Taylor DJ, Pruiksma KE, Acierno R, Larick JG, Baucom BRW, Garland EL, Rudd MD. Brief Cognitive Behavioral Therapy for Suicidal Military Personnel and Veterans: The Military Suicide Prevention Intervention Research (MSPIRE) Randomized Clinical Trial. JAMA Psychiatry. 2025 Oct 8:e252850. doi: 10.1001/jamapsychiatry.2025.2850. Online ahead of print.
Provided Documents
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Document Type: Informed Consent Form
Related Links
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Suicide and Trauma Reduction Initiative (STRIVE)
Other Identifiers
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W81XWH1820022
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
NMCCL.2018.0009
Identifier Type: -
Identifier Source: org_study_id