Attentional Bias Retraining in Veterans

NCT ID: NCT02041572

Last Updated: 2017-11-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-05-31

Study Completion Date

2015-06-30

Brief Summary

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The study has two goals. First to develop a computer-based intervention meant to alter cognitive biases that contribute to ongoing PTSD symptoms. Second, we sought to pilot test the intervention in a small sample of veterans for feasibility and acceptability.

Detailed Description

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Aim 1: Develop Attentional Bias Retraining protocol (Phase 1)

* 1.1 Computerized assessment \& retraining programs
* 1.2 Procedures and measures

Aim 2: Implement in pilot sample (Phase 2)

* 2.1: Assess feasibility and tolerability
* 2.2: Collect pilot data to plan future studies
* 2.3: Efficacy estimates based on changes in response time to dot probe task

Conditions

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Posttraumatic Stress Disorder

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

The transition point from the assessment only version of the attention bias program to the retraining/ bias correction version was randomized at the participant level and occurred between weeks 4 and 7 of the 10-week study.

Study Groups

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Attentional Bias Retraining

Each participant receives 12 sessions. The first three sessions are baseline (assessment only) sessions. The last four sessions must be treatment sessions. The attentional bias intervention starts randomly on sessions 4 - 8, and continues until the end of the 12 sessions.

Group Type OTHER

Attentional bias retraining

Intervention Type BEHAVIORAL

Participants complete a computer-based intervention, which is designed to correct cognitive biases associated with PTSD by training to attend to neutral information rather than the trauma-related cue words.

Interventions

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Attentional bias retraining

Participants complete a computer-based intervention, which is designed to correct cognitive biases associated with PTSD by training to attend to neutral information rather than the trauma-related cue words.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Participated in ground combat operations in Vietnam
* Scored 40 - 80 on PTSD Checklist - Military version
* Availability and willingness to attend 2x weekly computer sessions for 6 weeks

Exclusion Criteria

* Active substance dependence
* Significant cognitive impairment
* Current and active suicidal or homicidal ideation
Minimum Eligible Age

18 Years

Maximum Eligible Age

89 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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VA Pacific Islands Health Care System

FED

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Margaret-Anne Mackintosh, PhD

Role: PRINCIPAL_INVESTIGATOR

National Center for PTSD/PHREI

Locations

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National Center for PTSD

Honolulu, Hawaii, United States

Site Status

Countries

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United States

Other Identifiers

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2012-05/MM/PROMISE 0001

Identifier Type: -

Identifier Source: org_study_id