High vs Normal Protein Diets, Resistance Exercise, Lean Mass and Strength Gains

NCT ID: NCT03024125

Last Updated: 2017-01-18

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 20 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-05-31
• Study Completion Date: 2017-02-28

Brief Summary

This study evaluates the effect of different types of diets (high and normal protein) on lean and fat mass, and strength in postmenopausal women practitioners of resistance exercise. Two groups will be created: high protein (1.2 protein g/body mass/day) and normal protein (0.8 protein g/body mass/day). The same training will be performed for both groups.

Detailed Description

Both groups will undergo the same training protocol, differing only on the protein content of the diet. The dietary assessment will be made through the 24-hour food recall, being conducted at the beginning, middle and end of the intervention. Resistance exercises for upper and lower limbs will be performed, at 70% of one repetition maximum. SPPB, tug, 6-minutes and 400 meters will be performed.

Conditions

Sarcopenia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

High protein diet (HP)

Diet with 1.2 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups

Group Type: EXPERIMENTAL

High protein

Intervention Type: OTHER

To observe the effect of a high protein (HP) diet over muscle mass, fat mass, and strength changes, focusing in differences between the NP and HP groups.

Training

Intervention Type: OTHER

The physical strength training will be performed equally by both groups, containing exercises for upper and lower limbs and aiming for hypertrophy.

Normal protein diet (NP)

Diet with 0.8 protein g/kg body mass/day for postmenopausal women practitioners of resistance exercise. The physical strength training will be performed equally by both groups

Group Type: PLACEBO_COMPARATOR

Normal protein

Intervention Type: OTHER

To observe the effect of a normal protein (NP) diet over muscle mass, fat mass, and strength changes

Training

Intervention Type: OTHER

The physical strength training will be performed equally by both groups, containing exercises for upper and lower limbs and aiming for hypertrophy.

Interventions

High protein

To observe the effect of a high protein (HP) diet over muscle mass, fat mass, and strength changes, focusing in differences between the NP and HP groups.

Intervention Type: OTHER

Normal protein

To observe the effect of a normal protein (NP) diet over muscle mass, fat mass, and strength changes

Intervention Type: OTHER

Training

The physical strength training will be performed equally by both groups, containing exercises for upper and lower limbs and aiming for hypertrophy.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Women in the postmenopausal period (menopausal for at least one year, confirmed by laboratory diagnostic tests menopause - LH and high FSH and estradiol decreased);
• Healthy;
• Who agree to participate and sign the consent term.

Exclusion Criteria

• The one who does not provide the necessary information for the development of the study;
• Present orthopedic limitations;
• Patients with previously diagnosed and treatment of diseases such as type II diabetes mellitus, hypertension and cardiovascular disease.

• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Federal University of Uberlandia

OTHER

Sponsor Role: lead

Responsible Party

Erick Prado de Oliveira

PhD

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Erick P de Oliveira, PhD

Role: PRINCIPAL_INVESTIGATOR

Federal University of Uberlandia

References

Nahas PC, Rossato LT, Martins FM, Souza AP, de Branco FMS, Carneiro MAS, Teixeira KRC, Orsatti FL, de Oliveira EP. Moderate Increase in Protein Intake Promotes a Small Additional Improvement in Functional Capacity, But Not in Muscle Strength and Lean Mass Quality, in Postmenopausal Women Following Resistance Exercise: A Randomized Clinical Trial. Nutrients. 2019 Jun 13;11(6):1323. doi: 10.3390/nu11061323.

Reference Type: DERIVED

PMID: 31200437 (View on PubMed)

Rossato LT, Nahas PC, de Branco FMS, Martins FM, Souza AP, Carneiro MAS, Orsatti FL, de Oliveira EP. Higher Protein Intake Does Not Improve Lean Mass Gain When Compared with RDA Recommendation in Postmenopausal Women Following Resistance Exercise Protocol: A Randomized Clinical Trial. Nutrients. 2017 Sep 12;9(9):1007. doi: 10.3390/nu9091007.

Reference Type: DERIVED

PMID: 28895933 (View on PubMed)

Other Identifiers

1.733.512

Identifier Type: -

Identifier Source: org_study_id