Value of FLT PET/CT in Radium-223 Therapy of mCRPC Patients

NCT ID: NCT03011749

Last Updated: 2019-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

6 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-31

Study Completion Date

2018-02-28

Brief Summary

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The aim of the study is to investigate whether positron emission tomography (PET) using the tracer 18F-Fluorothymidine (FLT) can provide information on proliferative activity in bone marrow of patients receiving Radium 223 therapy and potentially be a predictive marker of hematological toxicity

Detailed Description

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Conditions

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Metastatic Prostate Carcinoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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FLT PET/CT

FLT PET/CT

Group Type EXPERIMENTAL

FLT PET/CT

Intervention Type OTHER

FLT PET/CT before first series of Radium-223 and after 2 series

Interventions

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FLT PET/CT

FLT PET/CT before first series of Radium-223 and after 2 series

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Metastatic castration resistant prostate cancer
* Eligible for Radium-223 therapy
* Informed consent

Exclusion Criteria

* Inability to understand study protocol
* Extensive metastatic involvement of the axial skeleton ("superscan" on bone scintigraphy)
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Rigshospitalet, Denmark

OTHER

Sponsor Role lead

Responsible Party

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Marie Øbro Fosbøl

MD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Rigshospitalet

Copenhagen, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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H1603551

Identifier Type: -

Identifier Source: org_study_id

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