Accuracy of Zero Heat Flux Cutaneous Temperature in Intensive Care Adults

NCT ID: NCT02931227

Last Updated: 2019-01-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-08-31

Study Completion Date

2018-06-30

Brief Summary

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Temperature is one of the vital signs usually monitored in patients of ICUs. Indeed, fever occurs frequently in ICU especially in brain injured patients and may require targeted temperature management (TTM) in special case as intracranial hypertension or post cardiac arrest. In ICU, non invasive device to monitor temperature are not recommended and only invasive ones are accurate enough for TTM. Arterial pulmonary temperature is still the gold standard, but esophageal device is currently used in ICU patients.

The goal of this study is to compare accuracy of a continuous noninvasive cutaneous temperature using zero-heat-flux (ZHF) method to esophageal temperature, arterial temperature and intracerebral temperature if present for clinical monitoring.

All adults patients admitted in the neurosurgical or surgical ICU are eligible for inclusion into this study.

Assessment of temperature will be continuously monitored by esophageal probe (MON-A-THERM, 12Fr, COVIDIEN, Dublin, Ireland) (Teso), ZHF sensor (SpotOn, 3M, St Paul, MN, USA) (TZHF) and, in patients requiring cardiac output monitoring, by femoral arterial catheter (Pulsiocath PICCO, PULSION, Munich, Germany) (Tart). The correct positioning of the esophageal probe will be controlled by chest X-ray. The ZHF temperature sensor (TZHF) will be placed on the forehead as recommend by the manufacturer and connected to the SpotOn monitor. Intra cerebral temperature (Tbrain) will be obtained with an intracranial probe used as calibrator for partial pressure of O2 in brain (PbO2, Licox®Combined Oxygen and Temperature Probe 462 mm device necessary for monitoring severe brain injured patients. The ZHF sensor will be changed every 24 hours according to the manufacturer's directions for use. Temperatures will be recorded automatically at a 5-minutes interval via the patient's monitor with an electronic data acquisition system (Data Collect, Phillips) for a maximum of 5 days.

For each patient included, data recorded will be: demographic and clinical particulars for each patient; information on hemodynamics, sedative, analgesic and inotropic agents, use of neuromuscular blockades and their indication, reason of hypo or hyperthermia (spontaneous or therapeutic), indication and the means used (neuromuscular blockades, external or internal cooling) in case of Targeted Temperature Management; complications related to the ZHF sensor application.

Detailed Description

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Conditions

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Continuous Non Invasive Cutaneous Temperature Zero Heat Flux Method Esophageal Temperature Arterial Temperature Intracerebral Temperature

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Brain-injured group

Group Type EXPERIMENTAL

temperature obtained by the non-invasive method of zero-heat flux

Intervention Type PROCEDURE

esophageal temperature

Intervention Type PROCEDURE

intracerebral temperature

Intervention Type PROCEDURE

Hypothermia group

Group Type EXPERIMENTAL

temperature obtained by the non-invasive method of zero-heat flux

Intervention Type PROCEDURE

esophageal temperature

Intervention Type PROCEDURE

intracerebral temperature

Intervention Type PROCEDURE

Hyperthermia group

Group Type EXPERIMENTAL

temperature obtained by the non-invasive method of zero-heat flux

Intervention Type PROCEDURE

esophageal temperature

Intervention Type PROCEDURE

intracerebral temperature

Intervention Type PROCEDURE

PICCO group

Group Type EXPERIMENTAL

temperature obtained by the non-invasive method of zero-heat flux

Intervention Type PROCEDURE

esophageal temperature

Intervention Type PROCEDURE

intracerebral temperature

Intervention Type PROCEDURE

arterial temperature

Intervention Type PROCEDURE

Interventions

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temperature obtained by the non-invasive method of zero-heat flux

Intervention Type PROCEDURE

esophageal temperature

Intervention Type PROCEDURE

intracerebral temperature

Intervention Type PROCEDURE

arterial temperature

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* minimum 18 years old
* patients who required core temperature monitoring

Exclusion Criteria

* front disrepair
* refusal to participate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Poitiers University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU de Poitiers

Poitiers, , France

Site Status

Countries

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France

Other Identifiers

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TempCore

Identifier Type: -

Identifier Source: org_study_id

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