China PEACE 5p-HF Study

NCT ID: NCT02878811

Last Updated: 2017-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-08-31

Study Completion Date

2019-06-30

Brief Summary

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The investigators will consecutively recruit 5000 patients hospitalized for heart failure (HF) from 50 hospitals across China and follow them up for one year, describe treatment patterns during hospitalization and the follow-ups, examine patients recovery trajectory after HF, and identify targets for care quality improvement.

Detailed Description

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This study will consecutively enroll patients with HF as the primary reason for hospitalization in 50 hospitals scattered all over China. Participants will be interviewed at baseline (i.e., during the index hospitalization for HF), and at 1, 6, and 12 months following hospital discharge. During the follow-up period, participants will be instructed to return to the hospital for interviews by site investigators. Telephone follow-ups will be conducted only when in-person interviews are not feasible.

At baseline, participants will be interviewed to collect detailed information about on demographics, socioeconomic status, cardiovascular risk factors, clinical characteristics, treatments, in-hospital outcomes, general and disease-specific quality of life, function and mental status; during the follow-ups, the investigators will collect information about clinical outcomes events, long-term treatments, function, quality of life, symptoms, and medical care during the recovery period.

The investigators will collect blood and urine samples during index hospitalization and the follow-ups.

This study will examine a series of factors that may affect patients' recovery after HF. Practical guidelines, quality evaluative system, and risk model will be established based on the findings, to improve patient outcomes in the future.

Conditions

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Heart Failure

Keywords

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heart failure prospective cohort

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Observational study

This is a non-interventional study, patients receive their usual treatment as determined by the physician.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Patients with heart failure as the primary reason for hospitalization, including both new-onset HF or decompensation of chronic HF
2. Aged 18 years or above

Exclusion Criteria

1. Patients who have enrolled in this study
2. Patients who usually do not live in the city/county where the index hospital locates
3. Patients who are unable to complete interviews due to severe conditions, mental illness, or communication difficulties.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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China National Center for Cardiovascular Diseases

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jing Li, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

China National Center for Cardiovascular Disease

Harlan M Krumholz, MD, SM

Role: PRINCIPAL_INVESTIGATOR

Yale University

Locations

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Xinxiang Central Hospital

Xinxiang, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Jing Li, MD, PhD

Role: CONTACT

Phone: +86 (10) 6086 6077

Email: [email protected]

Yuan Yu, MD

Role: CONTACT

Phone: +86 17801013954

Email: [email protected]

Facility Contacts

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Shuhong Su

Role: primary

References

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Li J, Lei L, Wang W, Li Y, Yu Y, Pu B, Peng Y, Huo X, Zhang L. Patient-reported health status vs. N-terminal pro-B-type natriuretic peptide levels in patients with acute heart failure. Chin Med J (Engl). 2025 Jul 22. doi: 10.1097/CM9.0000000000003555. Online ahead of print.

Reference Type DERIVED
PMID: 40693625 (View on PubMed)

Zhang L, Wang W, Peng Y, He G, Ji R, Lei L, Li J, Pu B, Liu Y, Yu Y, Zhang H. Associations of cumulative depressive symptoms within 1-year of discharge with subsequent mortality among patients hospitalized for acute heart failure: Findings from The China PEACE Prospective Heart Failure Study. J Affect Disord. 2024 Apr 15;351:299-308. doi: 10.1016/j.jad.2024.01.245. Epub 2024 Jan 28.

Reference Type DERIVED
PMID: 38290578 (View on PubMed)

Zhang L, He G, Huo X, Tian A, Ji R, Pu B, Peng Y. Long-Term Cumulative High-Sensitivity C-Reactive Protein and Mortality Among Patients With Acute Heart Failure. J Am Heart Assoc. 2023 Oct 3;12(19):e029386. doi: 10.1161/JAHA.123.029386. Epub 2023 Sep 30.

Reference Type DERIVED
PMID: 37776214 (View on PubMed)

Zhang L, Ji R, He G, Tian A, Huo X, Zheng Y, Qi L, Mi Y, Yan X, Wang B, Lei L, Li J, Liu J, Li J. Individual Trajectories of Health Status During the First Year of Discharge From Hospitalization for Heart Failure and Their Associations With Death in the Following Years. J Am Heart Assoc. 2023 Jul 18;12(14):e028782. doi: 10.1161/JAHA.122.028782. Epub 2023 Jul 8.

Reference Type DERIVED
PMID: 37421271 (View on PubMed)

Wang B, Lei L, Zhang H, Miao F, Zhang L, Tian A, Li J. Change in Depressive Symptoms During the First Month of Discharge and 1-Year Clinical Outcomes in Patients Hospitalized for Heart Failure. J Am Heart Assoc. 2022 Dec 20;11(24):e027438. doi: 10.1161/JAHA.122.027438. Epub 2022 Dec 14.

Reference Type DERIVED
PMID: 36515248 (View on PubMed)

Xing F, Zheng X, Zhang L, Hu S, Bai X, Hu D, Li B, Li J. Discharge heart rate and 1-year clinical outcomes in heart failure patients with atrial fibrillation. Chin Med J (Engl). 2022 Jan 5;135(1):52-62. doi: 10.1097/CM9.0000000000001768.

Reference Type DERIVED
PMID: 34982055 (View on PubMed)

Tian J, Zhao J, Zhang Q, Ren J, Han L, Li J, Zhang Y, Han Q. Assessment of chronic disease self-management in patients with chronic heart failure based on the MCID of patient-reported outcomes by the multilevel model. BMC Cardiovasc Disord. 2021 Jan 30;21(1):58. doi: 10.1186/s12872-021-01872-3.

Reference Type DERIVED
PMID: 33516189 (View on PubMed)

Huang X, Yu Y, Li X, Masoudi FA, Spertus JA, Yan X, Krumholz HM, Jiang L, Li J. The China Patient-centred Evaluative Assessment of Cardiac Events (PEACE) prospective heart failure study design. BMJ Open. 2019 Feb 19;9(2):e025144. doi: 10.1136/bmjopen-2018-025144.

Reference Type DERIVED
PMID: 30782925 (View on PubMed)

Other Identifiers

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2015BAI12B02-2

Identifier Type: -

Identifier Source: org_study_id