A Registry Study of Biomarkers in Progression of Acute Heart Failure(BIOMS-POAHF)

NCT ID: NCT04108182

Last Updated: 2019-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

850 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-12-31

Study Completion Date

2025-10-31

Brief Summary

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The registry study aims to discover the prognostic value of bio-markers in acute heart failure

Detailed Description

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Conditions

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Cardiovascular Diseases

Keywords

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heart failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* 1\. Patients aged greater than or equal to 18 years with acute exacerbation of chronic heart failure or new heart failure
* 2\. With typical symptoms of acute heart failure as follows: Dyspnea, ankle swelling and fatigue (Limited activity endurance), increased jugular pressure, rales and peripheral edema ;
* 3\. Plasma concentrations of BNP: BNP\>100pg/ML
* 4\. Echocardiography: Related structural heart disease (left ventricular hypertrophy and/or left atrial enlargement) and/or diastolic dysfunction

Exclusion Criteria

* 1\. Previous history of cancer or renal replacement therapy
* 2.Surgery was performed within a month
* 3.Accompanied by cardiogenic shock, sepsis, pneumonia
* 4.Eligible patients without informed consent form
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Institute of Heart, Lung and Blood Vessel Diseases

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jie Du, PHD

Role: STUDY_DIRECTOR

Beijing Anzhen Hospital

Locations

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Beijing Anzhen Hospital

Beijing, , China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yulin Li, PHD

Role: CONTACT

Email: [email protected]

Facility Contacts

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ke-xu Yang

Role: primary

References

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Ma K, Yang J, Shao Y, Li P, Guo H, Wu J, Zhu Y, Zhang H, Zhang X, Du J, Li Y. Therapeutic and Prognostic Significance of Arachidonic Acid in Heart Failure. Circ Res. 2022 Apr;130(7):1056-1071. doi: 10.1161/CIRCRESAHA.121.320548. Epub 2022 Mar 8.

Reference Type DERIVED
PMID: 35255710 (View on PubMed)

Other Identifiers

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BIOMS-POAHF

Identifier Type: -

Identifier Source: org_study_id