A Registry Study of Biomarkers in Heart Failure

NCT ID: NCT03784833

Last Updated: 2019-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-06-30

Study Completion Date

2024-06-30

Brief Summary

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The registry study aims to discover the prognostic value of bio-markers in heart failure

Detailed Description

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The purpose of this study is to investigate the prognostic value of biomarkers in Heart Failure.Patients with confirmed diagnosis of heart failure are enrolled.The primary outcome is all-cause mortality based on the death certificates. The secondary outcome is readmission for heart failure and all-cause mortality/readmission for heart failure according to the patients' medical records.

Conditions

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Cardiovascular Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age greater than or equal to 18 years at the time of admission to the hospital
* With symptoms of new-onset or worsening heart failure
* Received or is eligible to receive a principal hospital discharge diagnosis of HF
* With signs and syndromes as follows: dyspnea at rest or with minimal exertion (dyspnea, orthopnea, or edema);Rales, peripheral edema, ascites, or pulmonary vascular congestion on chest radiography.
* Patients who received packed red blood cells, whole blood, or platelets less than 10 days before the blood sample was taken;

Exclusion Criteria

* Have objective evidence of cardiac dysfunction documented either by plasma concentrations of BNP and/or N-terminal pro-brain natriuretic peptide (NT-proBNP) \<35 pg/mL or \<125 pg/ml, respectively
* Current known inability to follow instructions or comply with follow-up procedures.
* Eligible patients without informed consent form
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tianjin Medical University Second Hospital

OTHER

Sponsor Role collaborator

Second Affiliated Hospital of Wenzhou Medical University

OTHER

Sponsor Role collaborator

Beijing Luhe Hospital

OTHER

Sponsor Role collaborator

China-Japan Friendship Hospital

OTHER

Sponsor Role collaborator

Beijing Institute of Heart, Lung and Blood Vessel Diseases

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jie Du, Dr

Role: STUDY_DIRECTOR

The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart,Lung and Blood Vessel Diseases

Locations

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Beijing Anzhen Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yuan Wang, Dr

Role: CONTACT

13910161443

Bingbing Ke, Dr

Role: CONTACT

15510286857

Facility Contacts

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Yuan WANG, PhD

Role: primary

86-010-64456169

Other Identifiers

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BIOMS-HF

Identifier Type: -

Identifier Source: org_study_id

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