RCT to Evaluate Biocompatibility of Resin-based Dental Materials
NCT ID: NCT02874625
Last Updated: 2024-07-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
200 participants
INTERVENTIONAL
2017-08-30
2025-11-30
Brief Summary
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Urine and saliva samples will be taken for determination of bisphenol A levels at several time points, and for analysis of the estrogenic activity using ERE-CALUX.
Also buccal cells will be taken. Next, DNA extraction will be done with a commercial kit. Global alterations in DNA methylation and DNA hydroxymethylation levels will be determined using UPLC-MS/MS.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
SINGLE
Study Groups
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Treatment 1
Dental restoration performed with glass-ionomer materials.
Dental restoration
Teeth with caries will be restored
Treatment 2
Dental restoration performed with resin-based composites.
Dental restoration
Teeth with caries will be restored
Interventions
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Dental restoration
Teeth with caries will be restored
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
4 Years
10 Years
ALL
Yes
Sponsors
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KU Leuven
OTHER
Universitaire Ziekenhuizen KU Leuven
OTHER
Responsible Party
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Locations
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BIOMAT, Department of Oral Health Sciences
Leuven, , Belgium
Countries
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Facility Contacts
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Other Identifiers
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S57169
Identifier Type: -
Identifier Source: org_study_id
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