Dual Transversus Abdominis Plane Block in Pediatric Renal Transplant: Effect on Pain Control

NCT ID: NCT02858622

Last Updated: 2019-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-12-31

Study Completion Date

2019-03-31

Brief Summary

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Alleviating pain in children undergoing renal transplant is extremely challenging. Large incisions as those of renal transplant (Gibson's incision) require special techniques of pain control that don't affect hemodynamics or renal function. Since the transplant incision doesn't cross midline; a dual-TAP block is thought to be effective in providing pain control in such procedure as it will anesthetize the dermatomes T6-T12, the muscles of the anterior abdominal wall together with the underlying parietal peritoneum.

Detailed Description

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Conditions

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Renal Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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dual TAB group

22 patients will receive unilateral dual transversus abdominis plane (TAB) block USING bupivacaine 0.25% at a dose of 2 mg/kg

Group Type ACTIVE_COMPARATOR

bupivacaine

Intervention Type DRUG

bupivacaine 0.25% at a dose 2 mg/kg in the transversus abdominis plane

Pethidine

Intervention Type DRUG

pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia

perfalgan

Intervention Type DRUG

intravenous paracetamol

fentanyl

Intervention Type DRUG

control group

22 patients who will not receive dual TAB block

Group Type SHAM_COMPARATOR

Pethidine

Intervention Type DRUG

pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia

perfalgan

Intervention Type DRUG

intravenous paracetamol

fentanyl

Intervention Type DRUG

Interventions

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bupivacaine

bupivacaine 0.25% at a dose 2 mg/kg in the transversus abdominis plane

Intervention Type DRUG

Pethidine

pethidine intravenous at a dose 1mg/kg when pain score more than 5 postoperative rescue analgesia

Intervention Type DRUG

perfalgan

intravenous paracetamol

Intervention Type DRUG

fentanyl

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* 3-16 years
* end stage renal disease
* no known allergy to bupivacaine
* both sexes

Exclusion Criteria

* known allergy to bupivacaine
Minimum Eligible Age

3 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Sherif Mohamed Abd el moneim Soaida, MD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sherif M Soaida, M.D.

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Faculty of medicine, Cairo University

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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SMS2016-1

Identifier Type: -

Identifier Source: org_study_id

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