Evaluation of the Effectiveness of a Diagnostic Kit in the Etiological Diagnosis of Fevers of the Traveler

NCT ID: NCT02827175

Last Updated: 2023-04-21

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 110 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-01-07
• Study Completion Date: 2022-10-26

Brief Summary

Annually about 10 to 15 million international travelers from Europe visit tropical countries. Returning from a journey, fever is the cardinal symptom of many infections. This is the second reason for consultation (23%) for return from a trip, after digestive disorders (42%). Urgent evaluation must always be proposed. Although that may be the manifestation of a benign disease, fever of return can also presage a rapidly progressive and lethal disease. In 50% of cases, patients return home, after treatment and disappearance of symptoms, though the microorganism responsible for the pathology is not able to be identified. The prescription of a series of systematic biological examinations in the form of a diagnostic kit has shown its relevance and its effectiveness in improving the etiological diagnosis of endocarditis and pericardites for optimal support. In this study we propose to assess the effectiveness of the systematic prescription of a diagnostic kit 'fever of the traveler' to all patients hospitalized with a fever after returning from a trip. "Ready to use" kit brings together in a single bag (i) instructions for use, (ii) the tubes, bottles and jars for the etiological diagnosis of fever of the traveler in the usual support (iii) an additional blood tube for research of pathogens emerging.

Primary:

To assess the effectiveness of a diagnostic kit for the etiological diagnosis of fevers of travelers on the return.

Hypothesis:

Improvement of at least 15% of the etiological diagnosis of fevers of travelers on the return through the development of a diagnostic kit.

Conditions

Fevers of the Traveler

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: DIAGNOSTIC
• Blinding Strategy: NONE

Study Groups

fevers of the travelers

Group Type: EXPERIMENTAL

blood sample

Intervention Type: OTHER

Interventions

blood sample

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Patient with a T >38.5 ° C with or without associated clinical signs.
• Patient who traveled outside metropolitan France within 45 days with the hospitalization.
• Patient is more than 18 years old.
• Patient who accept to have his medical records reviewed for research.
• Patient with health insurance

Exclusion Criteria

• a feverish syndrome beyond 45 days after the return of their journey.
• a clinical symptomatologie on the return to journey without associated fever,
• minor(miner) ( 18 years).
• Pregnant or breast-feeding woman.
• Incapable major patient or outside state to express its consent.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assistance Publique Hopitaux De Marseille

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

catherine GEINDRE

Role: STUDY_DIRECTOR

Assistance Publique Hopitaux De Marseille

Locations

Asssitance Publique Hopitaux de Marseille

Marseille, , France

Countries

France

Other Identifiers

2013-A01536-39

Identifier Type: OTHER

Identifier Source: secondary_id

2013-45

Identifier Type: -

Identifier Source: org_study_id