tDCS Effects on Associative Learning in Younger Adults

NCT ID: NCT02795715

Last Updated: 2021-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-30

Study Completion Date

2018-12-31

Brief Summary

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The aim of this study is to investigate whether a tDCS-accompanied training of audio-visual associative memory leads to a performance improvement in healthy older individuals."

Detailed Description

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Conditions

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Associative Learning

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Anodal tDCS + training

Combination of intensive training of picture-word associations (Wernicko task) with anodal stimulation

Group Type EXPERIMENTAL

tDCS

Intervention Type DEVICE

training

Intervention Type BEHAVIORAL

Sham tDCS + training

Combination of intensive training of picture-word associations (Wernicko task) with sham stimulation

Group Type SHAM_COMPARATOR

tDCS

Intervention Type DEVICE

training

Intervention Type BEHAVIORAL

Interventions

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tDCS

Intervention Type DEVICE

training

Intervention Type BEHAVIORAL

Other Intervention Names

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intensive training of picture-word associations

Eligibility Criteria

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Inclusion Criteria

* Age: young (18-30 years)
* Right handedness
* unobtrusive neuropsychological screening

Exclusion Criteria

* Mild cognitive impairment (MCI) or other neurological diseases.
* History of severe alcoholism or use of drugs.
* Severe psychiatric disorders such as depression, psychosis (if not in remission) and severe untreated medical problems.
* Contraindication for MRI (claustrophobia, metallic implants, ferromagnetic metals in the body, disorders of thermoregulation, pregnant women).
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Agnes Flöel

Prof. Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Agnes Flöel, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

Charite University, Berlin, Germany

Locations

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Charité Universitätsmedizin Berlin

Berlin, , Germany

Site Status

Countries

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Germany

References

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Floel A, Rosser N, Michka O, Knecht S, Breitenstein C. Noninvasive brain stimulation improves language learning. J Cogn Neurosci. 2008 Aug;20(8):1415-22. doi: 10.1162/jocn.2008.20098.

Reference Type BACKGROUND
PMID: 18303984 (View on PubMed)

Breitenstein C, Knecht S. Development and validation of a language learning model for behavioral and functional-imaging studies. J Neurosci Methods. 2002 Mar 15;114(2):173-9. doi: 10.1016/s0165-0270(01)00525-8.

Reference Type BACKGROUND
PMID: 11856568 (View on PubMed)

Breitenstein C, Jansen A, Deppe M, Foerster AF, Sommer J, Wolbers T, Knecht S. Hippocampus activity differentiates good from poor learners of a novel lexicon. Neuroimage. 2005 Apr 15;25(3):958-68. doi: 10.1016/j.neuroimage.2004.12.019.

Reference Type BACKGROUND
PMID: 15808996 (View on PubMed)

Other Identifiers

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TRAINSTIM2.C

Identifier Type: -

Identifier Source: org_study_id

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