Gonadotropin Releasing Hormone Antagonist in Treatment of Early-onset Severe Ovarian Hyperstimulation Syndrome

NCT ID: NCT02784457

Last Updated: 2016-05-27

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE2
• Total Enrollment: 84 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-06-30
• Study Completion Date: 2016-03-31

Brief Summary

Efficacy of the use of GnRH antagonist in treatment of those who develop early-onset severe ovarian hyperstimulation syndrome and had cancelled embryo transfer

Conditions

Assisted Reproduction

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

GnRHant

women who received GnRH antagonist

Group Type: ACTIVE_COMPARATOR

Cetrorelix

Intervention Type: DRUG

Control

women who did not receive GnRH antagonist

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Cetrorelix

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Women who develop early-onset severe ovarian hyperstimulation syndrome after controlled ovarian stimulation using long GnRH agonist protocol and hCG for triggering ovulation.

Exclusion Criteria

• Women on short or antagonist protocols.
• Women who received GnRH agonist for triggering ovulation.
• Women who had embryo transfer.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 42 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Ain Shams University

OTHER

Sponsor Role: lead

Responsible Party

Mohammed Faris

Lecturer of Obstetrics and Gynecology

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

DAT-01

Identifier Type: -

Identifier Source: org_study_id