Assisted Hatching Versus Endometrial Scratch in Recurrent Implantation Failure
NCT ID: NCT02752568
Last Updated: 2016-04-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
300 participants
INTERVENTIONAL
2016-05-31
2016-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
FACTORIAL
TREATMENT
NONE
Study Groups
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Endometrial scratch group
endometrial scratch controlled ovarian hyperstimulation
endometrial scratch
midluteal endometrial scratch using Novak curette under general anesthesia in the cycle preceding stimulation
controlled ovarian hyperstimulation
using merional\&/ or fostimon doses individualized as judged by patient age \& ovarian reserve \& monitored by follicular size \& serum estradiol
Assisted hatching group
assisted hatching controlled ovarian hyperstimulation
assisted hatching
using Octax laser 20120644-laser 5452
controlled ovarian hyperstimulation
using merional\&/ or fostimon doses individualized as judged by patient age \& ovarian reserve \& monitored by follicular size \& serum estradiol
ovarian stimulation only group
controlled ovarian hyperstimulation
controlled ovarian hyperstimulation
using merional\&/ or fostimon doses individualized as judged by patient age \& ovarian reserve \& monitored by follicular size \& serum estradiol
Interventions
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endometrial scratch
midluteal endometrial scratch using Novak curette under general anesthesia in the cycle preceding stimulation
assisted hatching
using Octax laser 20120644-laser 5452
controlled ovarian hyperstimulation
using merional\&/ or fostimon doses individualized as judged by patient age \& ovarian reserve \& monitored by follicular size \& serum estradiol
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* normal uterine cavity by transvaginal ultrasound
Exclusion Criteria
* hydrosalpinx
* preimplantation genetic diagnosis
* severe male factor
18 Years
40 Years
FEMALE
No
Sponsors
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Kasr El Aini Hospital
OTHER
Responsible Party
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suzy abdelaziz Abdelhamid
lecturer of obstetrics & gynecology
Principal Investigators
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suzy abdelaziz, lecturer
Role: PRINCIPAL_INVESTIGATOR
kasrelaini hospital
Central Contacts
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References
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Lacey L, Hassan S, Franik S, Seif MW, Akhtar MA. Assisted hatching on assisted conception (in vitro fertilisation (IVF) and intracytoplasmic sperm injection (ICSI)). Cochrane Database Syst Rev. 2021 Mar 17;3(3):CD001894. doi: 10.1002/14651858.CD001894.pub6.
Other Identifiers
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ivfobgyn
Identifier Type: -
Identifier Source: org_study_id
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