Intrauterine Injection of Human Chorionic Gonadotropin Before Embryo Transfer in Women With Previous IVF Failure

NCT ID: NCT02329197

Last Updated: 2014-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

380 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-31

Study Completion Date

2016-03-31

Brief Summary

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Women with history of previous IVF cycle failure will be subjected to a fresh IVF cycle. At the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will be injected intrauterine by embryo transfer catheter 10 minutes before embryo transfer procedure.

Detailed Description

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Infertile women with history of previous IVF cycle failure will be subjected top a fresh IVF cycle. Following controlled ovarian hyperstimulation, ovum pick up and at the time they will be undergoing embryo transfer, 50 IU of human chorionic gonadotropins diluted in 0.025ml of tissue culture media will be injected intrauterine by embryo transfer catheter 10 minutes before embryo transfer procedure.

Conditions

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Infertility Invitro Fertilization

Keywords

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Infertility Invitro fertilization

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Group A

women undergoing IVF treatment will be subjected for intrauterine injection of 10 IU of human chorionic gonadotropin (HCG) (diluted in 0.025ml of tissue culture), 10 minutes before embryo transfer procedure.

Group Type EXPERIMENTAL

Human Chorionic Gonadotropin (HCG)

Intervention Type DRUG

intrauterine injection of HCG prior to embryo transfer in an IVF cycle

Group B

women undergoing IVF treatment will embryo transfer procedure performed in the standard way without intrauterine injection of HCG.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Human Chorionic Gonadotropin (HCG)

intrauterine injection of HCG prior to embryo transfer in an IVF cycle

Intervention Type DRUG

Other Intervention Names

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u-hCG

Eligibility Criteria

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Inclusion Criteria

\- women with previous IVF failure undergoing fresh IVF cycle

Exclusion Criteria

* women with hydrosalpinges women with intrauterine lesion like submucous fibroid or polyps
Minimum Eligible Age

19 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Mansoura University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Gibreel

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Ahmed Gibreel, MD

Role: PRINCIPAL_INVESTIGATOR

Mansoura University

Locations

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Mansoura University Teaching Hospital

Al Mansurah, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Ahmed Gibreel, MD

Role: CONTACT

Phone: 002/01004045733

Email: [email protected]

Other Identifiers

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H005

Identifier Type: -

Identifier Source: org_study_id