Does Local Injury of the Endometrium Improve Controlled Ovarian Hyperstimulation (COH) + Intrauterine Insemination (IUI) Outcome?
NCT ID: NCT01111799
Last Updated: 2012-03-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
600 participants
INTERVENTIONAL
2010-06-30
2012-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Clomiphene citrate + IUI + endometrial biopsy
Clomiphene citrate + IUI + endometrial biopsy
endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
Clomiphene citrate + IUI
No interventions assigned to this group
gonadotrophines + IUI + endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
gonadotrophines + IUI
No interventions assigned to this group
natural cycle + IUI + endometrail biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
natural cycle + IUI + endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
natural cycle + IUI
No interventions assigned to this group
Interventions
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endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
natural cycle + IUI + endometrial biopsy
two endometrial biopsies will be taken with a PIPELLE catheter on days 12 and 21 of the spontaneous menstrual cycle that precedes the fertility treatment.
Eligibility Criteria
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Inclusion Criteria
* infertility.
* patients undergoing IUI treatment.
* at least one failed IUI cycle.
Exclusion Criteria
* Known Pelvic inflammatory disease(PID).
18 Years
38 Years
FEMALE
No
Sponsors
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Meir Medical Center
OTHER
Responsible Party
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Principal Investigators
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Yuval Or, MD
Role: STUDY_DIRECTOR
Clalit health service
Locations
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Remez women medical center
Rehovot, , Israel
Countries
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Central Contacts
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Leila Aliger, MD
Role: CONTACT
Facility Contacts
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References
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Barash A, Dekel N, Fieldust S, Segal I, Schechtman E, Granot I. Local injury to the endometrium doubles the incidence of successful pregnancies in patients undergoing in vitro fertilization. Fertil Steril. 2003 Jun;79(6):1317-22. doi: 10.1016/s0015-0282(03)00345-5.
Other Identifiers
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004608K
Identifier Type: -
Identifier Source: org_study_id
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