FreeStyle Libre in Pregnancy Study

NCT ID: NCT02665455

Last Updated: 2017-12-05

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

83 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-31

Study Completion Date

2016-09-30

Brief Summary

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To evaluate the point accuracy of the FreeStyle Libre Flash Glucose Monitoring System when used at home by pregnant women with diabetes.

Detailed Description

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Conditions

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Diabetes Mellitus

Keywords

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Diabetes Mellitus Sensing Technology

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Intervention

FreeStyle Libre Flash Glucose Monitoring System

Group Type EXPERIMENTAL

FreeStyle Libre Flash Glucose Monitoring System

Intervention Type DEVICE

Subjects will wear the FreeStyle Libre Flash Glucose Monitoring System masked for 14 days.

During these 14 days subjects will be asked to perform 4 blood glucose tests (pre-meals and before bedtime) per day. At the same time as the blood glucose test a sensor scan is performed.

Interventions

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FreeStyle Libre Flash Glucose Monitoring System

Subjects will wear the FreeStyle Libre Flash Glucose Monitoring System masked for 14 days.

During these 14 days subjects will be asked to perform 4 blood glucose tests (pre-meals and before bedtime) per day. At the same time as the blood glucose test a sensor scan is performed.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Type 1, type 2 or Gestational Diabetes Mellitus (GDM) (confirmed diagnosis via Oral Glucose Tolerance Test (OGTT))
* Currently testing Blood Glucose(BG), on average at least 2 times per day
* Participant is ≥12+0 weeks gestation with a singleton pregnancy
* In the investigator's opinion, technically capable of using device

Exclusion Criteria

* Concomitant disease or condition that may compromise patient safety including and not limited to; cardiac disease or event, sickle cell disease, cystic fibrosis, severe mental illness, known or suspected eating disorder or any uncontrolled long term medical condition
* Currently receiving dialysis treatment or planning to receive dialysis during the study or, moderate to advanced nephropathy (serum creatinine ≥120 micromol/litre or total protein excretion exceeds 2 g/day or urinary albumin:creatinine ratio \>30 mg/mmol, estimated glomerular filtration rate (eGFR) may not be used)
* Diabetic Ketoacidosis (DKA) (in the previous 6 months)
* Known (or suspected) allergy to medical grade adhesives
* In the investigator's opinion the participant is unsuitable to participate due to any other cause/reason, considering guidelines (e.g. National Institute for Health and Care Excellence (NICE) and International Diabetes Federation(IDF)) for Diabetes in Pregnancy for HbA1c and Blood Pressure
* Experiencing any of the following conditions for current pregnancy:

* Pre-eclampsia
* HELLP syndrome (haemolysis, elevated liver enzymes and low platelet count)
* Prescribed Tocolytic drugs for treatment of preterm labour
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Abbott Diabetes Care

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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VIVIT-Institut am Akad. Lehrkrankenhaus Feldkirch, Innere Medizin und Kardiologie

Feldkirch, , Austria

Site Status

Medizinische Universität Graz

Graz, , Austria

Site Status

Medizinische Universität Wien

Vienna, , Austria

Site Status

Krankenhaus Hietzing mit Neurologischem Zentrum Rosenhügel

Vienna, , Austria

Site Status

Royal United Hospital

Bath, , United Kingdom

Site Status

Southmead Hospital

Bristol, , United Kingdom

Site Status

Cambridge University Hospitals NHS Foundation Trust

Cambridge, , United Kingdom

Site Status

St. James University Hospital, Leeds Teaching Hospitals NHS Trust

Leeds, , United Kingdom

Site Status

Manchester Royal Infirmary

Manchester, , United Kingdom

Site Status

James Cook University Hospital

Middlesbrough, , United Kingdom

Site Status

John Radcliffe Hospital

Oxford, , United Kingdom

Site Status

Derriford Hospital

Plymouth, , United Kingdom

Site Status

Warwick Hospital

Warwick, , United Kingdom

Site Status

Countries

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Austria United Kingdom

Other Identifiers

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ADC-UK-VAL-15026

Identifier Type: -

Identifier Source: org_study_id