Study to Describe Real World Drug Retention Rate of the Tocilizumab at One Year
NCT ID: NCT02608112
Last Updated: 2020-02-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
291 participants
OBSERVATIONAL
2015-12-31
2018-07-26
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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Participants with Moderate to Severe RA
Participants with moderate or severe RA, naïve to TCZ treatment (IV or SC), and who have no contra-indication to TCZ SC therapy as per the local label are included.
Methotrexate
Administered as per investigator's discretion. Investigator could also suggest any other csDMARDs instead of methotrexate.
Tocilizumab
Tocilizumab treatment will be administered SC at the discretion of the investigator in accordance with local clinical practice and local labelling.
Interventions
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Methotrexate
Administered as per investigator's discretion. Investigator could also suggest any other csDMARDs instead of methotrexate.
Tocilizumab
Tocilizumab treatment will be administered SC at the discretion of the investigator in accordance with local clinical practice and local labelling.
Eligibility Criteria
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Inclusion Criteria
* Participants with moderate to severe RA not previously treated with TCZ (Intravenous \[IV\] or SC) for whom the rheumatologists have decided to initiate TCZ SC treatment as monotherapy or in combination with another conventional synthetic disease modifying anti-rheumatic drugs (csDMARD)
Exclusion Criteria
* Participants with a contra-indication to TCZ SC therapy
18 Years
ALL
No
Sponsors
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Hoffmann-La Roche
INDUSTRY
Responsible Party
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Principal Investigators
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Clinical Trials
Role: STUDY_DIRECTOR
Hoffmann-La Roche
Locations
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Hopital Nord; Rhumatologie
Amiens, , France
Ch D Ardeche Meridionale; Medecine A2
Aubenas, , France
Ch De Belfort; Rhumatologie
Belfort, , France
Institut Calot Helio Marin; Rhumatologie
Berck, , France
Hopital Jean Minjoz
Besançon, , France
Hopital Pellegrin; Rhumatologie
Bordeaux, , France
Hopital La Cavale Blanche; Rhumatologie
Brest, , France
Hopital Cote De Nacre; Rhumatologie
Caen, , France
CH Jean Rougier; Rhumato Reed Fonctionnelle
Cahors, , France
Infirmerie Protestante; Medecine interne Cancerologie
Caluire-et-Cuire, , France
Hopital Pierre Nouveau;Medecine C Unite Rhumatologie
Cannes, , France
Cabinet medical,Rhumatologie
Castelnaudary, , France
Hopital Trousseau; Rhumatologie
Chambray-lès-Tours, , France
HIA PERCY; Medecine Interne
Clamart, , France
Hopital Gabriel Montpied; Service de Rhumatologie
Clermont-Ferrand, , France
CH compiègne
Compiègne, , France
Centre Hospitalier Alpes
Contamine-sur-Arve, , France
Chu Sud Francilien; Rhumatologie
Corbeil-essones, , France
CH Sud Francilien; Rhumatologie
Corbeil-Essonnes, , France
Hopital Henri Mondor; Rhumatologie
Créteil, , France
CH de Dax
Dax, , France
Ch De Douai; Medecine Polyvalente
Dechy, , France
Ch Louis Pasteur; Rhumato Med Interne Neurologie
Dole, , France
Hopital Victor Jousselin; Rhumatologie 4EME Sud
Druex, , France
Hopital Sud; Rhumatologie
Échirolles, , France
Chi Alpes Du Sud Site De Gap; Med Interne Et Polyvalente
Gap, , France
Cabinet Medical.
Haguenau, , France
Cabinet Medical
Haguenau, , France
Cabinet medical; Rhumatologie
Joué-lès-Tours, , France
CH de Juvisy sur Orge; Consult. externes
Juvisy-sur-Orge, , France
Cabinet
La Madeleine, , France
Hopital La Source; Rhumatologie
La Source, , France
Ch De Laon; Medecine Interne
Laon, , France
Ch Louis Pasteur; Medecine B3
Le Coudray, , France
CH de Bicêtre; Rhumatologie
Le Kremlin-Bicêtre, , France
Hopital Emile Roux; Rhumatologie
Le Puy-en-Velay, , France
Hopital B Roger Salengro; Rhumatologie
Lille, , France
Cabinet medical.
Lille, , France
Hopital Dupuytren; Rhumatologie
Limoges, , France
Cabinet de Rhumatologie MSP de Beaublanc
Limoges, , France
Ctre De Rhumato Lyon Presqu ile
Lyon, , France
Hopital Edouard Herriot; Pavillon F Rhumatologie
Lyon, , France
Hopital Sainte Marguerite; Rhumatologie
Marseille, , France
Fondation Hopital Saint Joseph; Rhumatologie
Marseille, , France
CH Annecy Genevois; Rhumatologie
Metz-Tessy, , France
GHI Le Raincy Montfermeil
Montfermeil, , France
Cabinet medical; Cabinet medical
Montpellier, , France
Cabinet Medical
Montpellier, , France
Hopital Lapeyronie; Immunologie Rhumatologie
Montpellier, , France
Hôpital Lapeyronie; Immuno-Rhumatologie Pr Jorgensen
Montpellier, , France
Ch Des Pays De Morlaix; Medecine I
Morlaix, , France
Cabinet Medical
Nice, , France
Hopital Pasteur; Rhumatologie
Nice, , France
Maison de Santé; MSP
Nogent-le-Rotrou, , France
Ch Pitie Salpetriere; Rhumatologie
Paris, , France
Hopital De La Croix Saint Simon; Medecine Interne Rhumatologie
Paris, , France
Ch Lyon Sud; Rhumato Secteur Jules Courmont
Pierre-Bénite, , France
Cabinet
Poitiers, , France
Chu La Miletrie; Rhumatologie
Poitiers, , France
Hopital Sud Anne de Bretagne; Rhumatologie
Rennes, , France
Hôpital Victor Provo
Roubaix, , France
Centre Medico-Chirurgical de Touraine
Saint-Cyr-sur-Loire, , France
Cabinet Medical
Saint-Lô, , France
Hopital Instruction Armees Begin; Rhumatologie
Saint-Mandé, , France
Centre Hopsitalier Saint Nazaire; Medecine Polyvalente
Saint-Nazaire, , France
Hopital Nord; Rhumatologie
Saint-Priest-en-Jarez, , France
Centre Hospitalier Saint Quentin
Saint-Quentin, , France
CH de Saint Quentin
Saint-Quentin, , France
Centre medical des coteaux; Rhumatologie
Saintes, , France
Hopital Hautepierre; Rhumatologie
Strasbourg, , France
Hopitaux du Leman site Thonon; Rhumatologie
Thonon-les-Bains, , France
Cabinet de Rhumatologie
Toulouse, , France
Hopital Purpan; Rhumatologie
Toulouse, , France
Cabinet Medical
Tours, , France
Cabinet Medical
Valenciennes, , France
Hopitaux De Brabois; Rhumatologie
Vandœuvre-lès-Nancy, , France
Hopital; Pole geriatrique
Villeneuve-sur-Lot, , France
Countries
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References
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Hilliquin P, Barnetche T, Baillet A, Flipo RM, Lespessailles E, Roux C, Fardellone P, Gilbert-Marceau A, Idier I, Constantin A, Shipley E, Baudens G, Saraux A. Real-World 1-Year Retention Rate of Subcutaneous Tocilizumab Treatment in Patients with Moderate to Severe Active Rheumatoid Arthritis: TANDEM Study. Rheumatol Ther. 2021 Mar;8(1):95-108. doi: 10.1007/s40744-020-00253-0. Epub 2020 Nov 20.
Other Identifiers
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ML29256
Identifier Type: -
Identifier Source: org_study_id
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