A Comparison of Colonic Bile Acid Content Following Right and Left Colectomies

NCT ID: NCT02596516

Last Updated: 2015-11-06

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2015-12-31
• Study Completion Date: 2020-12-31

Brief Summary

The aim of this study is to evaluate whether there is a difference in the bile acid content in the bowel in patients after right versus left colectomy. There is compelling evidence that patients under going resection of the right colon versus left coolon have a lower polyp detection rate in surveillance colonoscopies. The investigators intend to evaluate feces of patients undergoing left and right colectomies; prior to their surgery and again three and six months aftet the surgery. The investigators plan to compare the content of the different bile acids and to compare the content between the two groups.

Conditions

Colectomy; Bile Acid and Salts

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Age above 18.
• Patients intended to undergo a colectomy for colonic cancer
• Patients willing and participate and able to sign an informed consent

Exclusion Criteria

• Age under 18.
• Patients with Inflammatory Bowel Disease (Crohn's, Ulcerative colitis).
• Patients refusing to participate or are unable to understand or sign an informed consent

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Meir Medical Center

OTHER

Sponsor Role: lead

Responsible Party

Ilan Kent

Medical Doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

MMC-0249-15

Identifier Type: -

Identifier Source: org_study_id