Cardiac Output Measurement With NICCOMO and PiCCO Devices at Different PEEP Levels

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2021-03-31

Brief Summary

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Thermodilution cardiac output measurement is a reliable method, but it is an invasive one. PiCCO device requires cannulation of central vein and peripheral artery. Impedance method requires only attachment of special electrodes. Non-invasive methods are less accurate. Aim of study is to assess accuracy and reliability of impedance method ( using NICCOMO device) in comparison of thermodilution method ( using PiCCO device) at different PEEP levels.

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Detailed Description

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Echocardiography is performed prior to measurement to exclude patients with heart valve abnormalities.

Patients without spontaneous ventilation ( deeply unconscious, sedated or sedated and paralysed), ventilated with controlled mechanical ventilation mode with tidal volume 6-8 ml/ideal body weight, resulting in EtCO2 35-45 mmHg, with PiCCO catheters implemented have additionally NICCOMO device attached. Fraction of inspired oxygen (FiO2) is set to achieve saturation \>96% at positive end expiratory pressure (PEEP) 0 cmH2O.

Measurement of cardiac output are performed on expiration at PEEP 0, 5, 10, 15 20 cmH2O and at optimal PEEP (obtained from P-V curve). Simultaneously CO value from impedance device is noted. Other haemodynamic parameters, calculated by both devices are also noted - stroke volume (SV), stroke volume variation (SVV), Cardiac index (CI), systemic vascular resistance (SVR), systemic vascular resistance index (SVRI).

Conditions

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Cardiovascular Diagnostic Techniques

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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haemodynamics measuring

those with already implemented PICCO device get impedance device (NICCOMO) attached

PICCO

Intervention Type DEVICE

measurements based on thermodilution

NICCOMO

Intervention Type DEVICE

measurements based on impedance

Interventions

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PICCO

measurements based on thermodilution

Intervention Type DEVICE

NICCOMO

measurements based on impedance

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* critically ill patients
* patients on mechanical ventilation
* circulatory insufficiency (present or in the past) monitored with with PiCCO device

Exclusion Criteria

* morbid obesity,
* short neck,
* severe pneumonia,
* inability to NICCOMO electrodes attachment,
* massive tissue oedema,
* non-sinus cardiac rhythm,
* tachycardia,
* low cardiac output,
* septic shock,
* heart valve pathologies,
* severe atherosclerosis,
* aortic prosthesis,
* severe hypertension,
* extremes of height and weight,
* intraaortic pump

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No