Comparison of Different Cardiac Output Measurement Methods in Patients Undergoing Right Heart Catheterization
NCT ID: NCT05665218
Last Updated: 2022-12-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
1 participants
OBSERVATIONAL
2022-01-01
2024-12-31
Brief Summary
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The main questions it aims to answer are:
* Are these methods interchangeable?
* Can possible discrepancies influence risk stratification and therapeutic management of PH patients? All consecutive patients aged ≥18 years, referred for RHC for suspected PH, will be included. Exclusion criteria will be contraindications to RHC, cardiac shunts and failure to obtain informed consent. Patients will undergo RHC by a Swan-Ganz catheter through the right internal jugular vein ultrasound-guided cannulation and cardiac output will be calculated using the three above-mentioned methods.
Detailed Description
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Conditions
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Study Design
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CASE_ONLY
PROSPECTIVE
Study Groups
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patients undergoing right heart catheterization
right heart catheterization
Right heart catheterization (RHC) is an invasive hemodynamic procedure that allows direct measurement of right-sided cardiac pressures, calculation of cardiac output and pulmonary vascular resistance. It is the gold standard for the diagnosis of pulmonary arterial hypertension. Right heart catheterization is commonly performed by accessing the internal jugular vein (echo-guided access). Swan Ganz catheter with a dedicated thermistor is used to perform RHC; it is advanced through the right heart chambers to measure right atrial, right ventricle, pulmonary artery and pulmonary arterial wedge pressures. Cardiac output is measured using Fick direct, Fick indirect and thermodilution methods.
Interventions
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right heart catheterization
Right heart catheterization (RHC) is an invasive hemodynamic procedure that allows direct measurement of right-sided cardiac pressures, calculation of cardiac output and pulmonary vascular resistance. It is the gold standard for the diagnosis of pulmonary arterial hypertension. Right heart catheterization is commonly performed by accessing the internal jugular vein (echo-guided access). Swan Ganz catheter with a dedicated thermistor is used to perform RHC; it is advanced through the right heart chambers to measure right atrial, right ventricle, pulmonary artery and pulmonary arterial wedge pressures. Cardiac output is measured using Fick direct, Fick indirect and thermodilution methods.
Eligibility Criteria
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Inclusion Criteria
* Suspected pulmonary hypertension at clinical and echocardiographic evaluation
Exclusion Criteria
* cardiac shunt
* inability to provide informed consent
18 Years
ALL
No
Sponsors
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UOSD Emodinamica Diagnostica e Interventistica
OTHER
Responsible Party
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Livio Giuliani
Livio Giuliani MD, PhD
Principal Investigators
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Livio Giuliani, MD PhD
Role: PRINCIPAL_INVESTIGATOR
Interventional Cardiology Unit, SS Annunziata Hospital, Chieti
Locations
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UOSD Emodinamica Diagnostica e Interventistica Ospedale SS Annunziata
Chieti, , Italy
Countries
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Central Contacts
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Facility Contacts
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Livio Giuliani, MD PhD
Role: primary
Serena Rossi, MD
Role: backup
Other Identifiers
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CH2022-01
Identifier Type: -
Identifier Source: org_study_id