Propofol Versus Dexmedetomidine for Prevention of Sevoflurane Agitation in Recipients of Living Donor Liver Transplantation

NCT ID: NCT02544906

Last Updated: 2015-09-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-09-30

Study Completion Date

2016-10-31

Brief Summary

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The use of propofol or dexmedetomedine for prevention of sevofurane emergence agitation in LDLT recipients

Detailed Description

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Conditions

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Liver Transplantation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Control

No drugs will be given. the emergence agitation will be monitored and recorded

Group Type NO_INTERVENTION

No interventions assigned to this group

Propofol group

Propofol at dose of 1 mg/kg over 5 minutes will be started before extubation. the emergence agitation will be monitored and recorded

Group Type EXPERIMENTAL

Propofol

Intervention Type DRUG

Infusion of propofol to prevent emergence agitation in liver transplanta recipients

dexmedetomedine group

dexmedetomedine at dose of .5 mic/kg over 5 minutes will be started before extubation. the emergence agitation will be monitored and recorded

Group Type EXPERIMENTAL

dexmedetomedine

Intervention Type DRUG

Infusion of dexmedetomedine to prevent emergence agitation in liver transplanta recipients

Interventions

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Propofol

Infusion of propofol to prevent emergence agitation in liver transplanta recipients

Intervention Type DRUG

dexmedetomedine

Infusion of dexmedetomedine to prevent emergence agitation in liver transplanta recipients

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* All recipients of living donor liver transplantation

Exclusion Criteria

* patient refusal Allergy to either propofol or dexmedetomediene CNS disease
Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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AlRefaey Kandeel

OTHER

Sponsor Role lead

Responsible Party

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AlRefaey Kandeel

Dr

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Mansoura university

Al Mansurah, Dkahleya, Egypt

Site Status

Countries

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Egypt

Facility Contacts

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Alreafey Kandeel, MD

Role: primary

00201008158591

Other Identifiers

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LTx 7

Identifier Type: -

Identifier Source: org_study_id

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