Gait Asymmetry Assessed Using Portable Gait Analysis System

NCT ID: NCT02489188

Last Updated: 2019-11-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-06-30

Study Completion Date

2019-09-30

Brief Summary

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To date, detailed analysis of movement patterns in orthopaedic conditions are mainly performed in research projects. Because these tests are time consuming, they are not feasible in clinical routine or in standard examinations. Novel technologies allow capturing detailed movement patters within a few minutes. The aim of this regional study is to compare aspects of movement tasks measured using a mobile gait analysis system to those measured using laboratory based systems and to determine aspects of gait patterns relevant for different orthopaedic conditions. Moreover, the researchers will investigate if these relevant aspects can be altered using surgical treatment or manual therapy.

Detailed Description

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This is a cross-sectional study. Pre- and post-treatment data will only be collected in patients undergoing routine orthopaedic treatment.

Conditions

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Ankle Osteoarthritis Knee Osteoarthritis Hip Osteoarthritis Lumbar Spine Stenosis Muscle Contracture

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ankle osteoarthritis

patients with ankle osteoarthritis scheduled for arthroplasty

arthroplasty

Intervention Type PROCEDURE

patients, who are scheduled for arthroplasty, will be measured before and on average 6 months after surgery

manual therapy

Intervention Type OTHER

patients, who are scheduled for manual therapy, will be measured before, immediately and on average 1 week after treatment

knee osteoarthritis

patients with knee osteoarthritis scheduled for arthroplasty

arthroplasty

Intervention Type PROCEDURE

patients, who are scheduled for arthroplasty, will be measured before and on average 6 months after surgery

manual therapy

Intervention Type OTHER

patients, who are scheduled for manual therapy, will be measured before, immediately and on average 1 week after treatment

hip osteoarthritis

patients with hip osteoarthritis scheduled for arthroplasty

arthroplasty

Intervention Type PROCEDURE

patients, who are scheduled for arthroplasty, will be measured before and on average 6 months after surgery

manual therapy

Intervention Type OTHER

patients, who are scheduled for manual therapy, will be measured before, immediately and on average 1 week after treatment

lumbar spinal stenosis

patients with lumbar spinal stenosis scheduled for lumbar spinal stenosis decompression

manual therapy

Intervention Type OTHER

patients, who are scheduled for manual therapy, will be measured before, immediately and on average 1 week after treatment

lumbar spinal stenosis decompression

Intervention Type PROCEDURE

patients, who are scheduled for lumbar spinal stenosis decompression, will be measured before and on average 6 months after surgery

muscle contracture

patients with functionally limited range of motion at the knee because of muscle contracture scheduled for manual therapy

manual therapy

Intervention Type OTHER

patients, who are scheduled for manual therapy, will be measured before, immediately and on average 1 week after treatment

healthy subjects

healthy subjects

No interventions assigned to this group

Interventions

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arthroplasty

patients, who are scheduled for arthroplasty, will be measured before and on average 6 months after surgery

Intervention Type PROCEDURE

manual therapy

patients, who are scheduled for manual therapy, will be measured before, immediately and on average 1 week after treatment

Intervention Type OTHER

lumbar spinal stenosis decompression

patients, who are scheduled for lumbar spinal stenosis decompression, will be measured before and on average 6 months after surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 40 years, for patients: diagnosed osteoarthritis at the ankle, knee or hip, lumbar spinal stenosis or limited range of motion at the knee

Exclusion Criteria

* Body mass index \> 35kg/m2
* Use of walking aids
* Inability to walk for 6 minutes
* Neuromuscular disorders affecting gait
* Cardiovascular disease
* Inability to follow procedures due to psychological disorders or dementia
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Annegret Mündermann, PhD

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Basel, Switzerland

Locations

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University Hospital Basel

Basel, Canton of Basel-City, Switzerland

Site Status

Countries

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Switzerland

References

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Horstmann T, Listringhaus R, Haase GB, Grau S, Mundermann A. Changes in gait patterns and muscle activity following total hip arthroplasty: a six-month follow-up. Clin Biomech (Bristol). 2013 Aug;28(7):762-9. doi: 10.1016/j.clinbiomech.2013.07.001. Epub 2013 Jul 29.

Reference Type BACKGROUND
PMID: 23906936 (View on PubMed)

Horstmann T, Listringhaus R, Brauner T, Grau S, Mundermann A. Minimizing preoperative and postoperative limping in patients after total hip arthroplasty: relevance of hip muscle strength and endurance. Am J Phys Med Rehabil. 2013 Dec;92(12):1060-9. doi: 10.1097/PHM.0b013e3182970fc4.

Reference Type BACKGROUND
PMID: 23739275 (View on PubMed)

Horstmann T, Vornholt-Koch S, Brauner T, Grau S, Mundermann A. Impact of total hip arthroplasty on pain, walking ability, and cardiovascular fitness. J Orthop Res. 2012 Dec;30(12):2025-30. doi: 10.1002/jor.22163. Epub 2012 May 31.

Reference Type BACKGROUND
PMID: 22653634 (View on PubMed)

Mundermann A, Mundermann L, Andriacchi TP. Amplitude and phasing of trunk motion is critical for the efficacy of gait training aimed at reducing ambulatory loads at the knee. J Biomech Eng. 2012 Jan;134(1):011010. doi: 10.1115/1.4005540.

Reference Type BACKGROUND
PMID: 22482665 (View on PubMed)

Mundermann A, Asay JL, Mundermann L, Andriacchi TP. Implications of increased medio-lateral trunk sway for ambulatory mechanics. J Biomech. 2008;41(1):165-70. doi: 10.1016/j.jbiomech.2007.07.001. Epub 2007 Aug 3.

Reference Type BACKGROUND
PMID: 17678933 (View on PubMed)

Fisher DS, Dyrby CO, Mundermann A, Morag E, Andriacchi TP. In healthy subjects without knee osteoarthritis, the peak knee adduction moment influences the acute effect of shoe interventions designed to reduce medial compartment knee load. J Orthop Res. 2007 Apr;25(4):540-6. doi: 10.1002/jor.20157.

Reference Type BACKGROUND
PMID: 17205556 (View on PubMed)

Mundermann A, Dyrby CO, Andriacchi TP. Secondary gait changes in patients with medial compartment knee osteoarthritis: increased load at the ankle, knee, and hip during walking. Arthritis Rheum. 2005 Sep;52(9):2835-44. doi: 10.1002/art.21262.

Reference Type BACKGROUND
PMID: 16145666 (View on PubMed)

Mundermann A, Dyrby CO, Hurwitz DE, Sharma L, Andriacchi TP. Potential strategies to reduce medial compartment loading in patients with knee osteoarthritis of varying severity: reduced walking speed. Arthritis Rheum. 2004 Apr;50(4):1172-8. doi: 10.1002/art.20132.

Reference Type BACKGROUND
PMID: 15077299 (View on PubMed)

Nuesch C, Huber C, Paul J, Henninger HB, Pagenstert G, Valderrabano V, Barg A. Mid- to Long-term Clinical Outcome and Gait Biomechanics After Realignment Surgery in Asymmetric Ankle Osteoarthritis. Foot Ankle Int. 2015 Aug;36(8):908-18. doi: 10.1177/1071100715577371. Epub 2015 Mar 20.

Reference Type BACKGROUND
PMID: 25795650 (View on PubMed)

Nuesch C, Valderrabano V, Huber C, Pagenstert G. Effects of supramalleolar osteotomies for ankle osteoarthritis on foot kinematics and lower leg muscle activation during walking. Clin Biomech (Bristol). 2014 Mar;29(3):257-64. doi: 10.1016/j.clinbiomech.2013.12.015. Epub 2013 Dec 31.

Reference Type BACKGROUND
PMID: 24445126 (View on PubMed)

Nuesch C, Barg A, Pagenstert GI, Valderrabano V. Biomechanics of asymmetric ankle osteoarthritis and its joint-preserving surgery. Foot Ankle Clin. 2013 Sep;18(3):427-36. doi: 10.1016/j.fcl.2013.06.002. Epub 2013 Jul 24.

Reference Type BACKGROUND
PMID: 24008209 (View on PubMed)

Nuesch C, Valderrabano V, Huber C, von Tscharner V, Pagenstert G. Gait patterns of asymmetric ankle osteoarthritis patients. Clin Biomech (Bristol). 2012 Jul;27(6):613-8. doi: 10.1016/j.clinbiomech.2011.12.016. Epub 2012 Jan 18.

Reference Type BACKGROUND
PMID: 22261013 (View on PubMed)

Other Identifiers

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2015-139

Identifier Type: -

Identifier Source: org_study_id

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