Non-invasive Ventilation in Patients With Interstitial Lung Disease

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2019-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The efficiency of non-invasive ventilation (NIV) in hypercapnic patients with chronic obstructive pulmonary disease during pulmonary rehabilitation has been shown in numerous studies. There is only a limited number of therapeutic options for patients with severely progressed interstitial lung disease (ILD). The question whether chronic hypercapnic ILD-patients are able to profit from nocturnal NIV and thus increase their performance in physical training has been left unknown. Therefore, this study aims to evaluate the feasibility of the initialization of a NIV for hypercapnic ILD-patients during pulmonary rehabilitation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effects of Nocturnal Non-invasive Ventilation in Stable COPD

NCT03053973

Noninvasive Ventilation

RECRUITING NA

Non-invasive Ventilation in Severe Chronic Obstructive Pulmonary Disease(COPD)

NCT00710541

Chronic Obstructive Pulmonary Disease Hypercapnia

TERMINATED NA

Course and Complications of Invasive Out-of-hospital Ventilation

NCT01755039

Indication for Invasive Out-of-hospital Ventilation

COMPLETED

Non Invasive Mechanical Ventilation in Chronic Respiratory Insufficiency Patients During Rehabilitation

NCT01458314

Chronic Respiratory Insufficiency

COMPLETED NA

Deventilation Dyspnea in COPD Patients Using NIV

NCT03503123

COPD Dyspnea Mechanical Ventilation Complication

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Noninvasive Ventilation Lung Diseases, Interstitial

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

non-invasive ventilation

patients will undergo about 14 nights of non-invasive ventilation during pulmonary rehabilitation

Group Type EXPERIMENTAL

non-invasive ventilation

Intervention Type OTHER

patients will undergo a nocturnal non-invasive ventilation

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

non-invasive ventilation

patients will undergo a nocturnal non-invasive ventilation

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* confirmed diagnosis of Interstitial lung disease
* Hypercapnia defined as carbon dioxide partial pressure ≥45 mmHg (at rest, night or activity)
* already existing but not sufficient and regular use of non-invasive ventilation (≤3h/24h)
* patients consent to participate in this trial

Exclusion Criteria

* acute pulmonary insufficiency (ph\<7.35)
* acute, clinically relevant heart disease
* already existing and sufficient use of non-invasive ventilation (≥3h/24h)
* Body-Mass-Index\>30
* obstructive sleep apnea
* Intolerance to perform non-invasive ventilation
* acute infection

Eligible Sex

ALL

Accepts Healthy Volunteers

No