Magnetic Resonance Imaging to Assess Changes in Meniscus Vascularity

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-06-30

Brief Summary

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The menisci in the knee joint are important for normal functioning of the knee. Meniscus tears are amongst the commonest of injuries to the knee. The pattern and blood supply of the meniscus tears determines the treatment plan and outcome. The surgeon identifies the blood supply to the meniscus tear area during the arthroscopy(key hole operation) and decides the treatment option ie repair versus partial meniscectomy.

This study aims to identify any changes that occur in the meniscus blood supply. The following are the main aims of the 'MOVE'study-

1. Use of non-invasive methods ie MRImaging to assess meniscus vascularity to preoperatively plan treatment and advice patient on recovery.
2. The study would assess changes in meniscus blood supply depending on age of the patient.
3. The study aims to assess the alteration in meniscus blood supply following an arthroscopic(key hole) meniscal repair operation.

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Detailed Description

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Conditions

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Meniscus Tears

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Study Groups

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Group One patients in age group 18--20 years,

1. Patients should be aged 18--20 years or 35--45years
2. Asymptomatic knee for past 6 months.
3. Painless flexion-extension movements at knee joint.

Group Type NO_INTERVENTION

No interventions assigned to this group

Group Two patients in age group 35-45 years,

1. Patients should be aged 18--20 years or 35--45years
2. Asymptomatic knee for past 6 months.
3. Painless flexion-extension movements at knee joint.

Group Type ACTIVE_COMPARATOR

Will undergo a single MRI assessment with intravenous dye

Intervention Type OTHER

Group Three Patients aged 75

1. Patients should be aged 75 or older
2. Knee X-ray showing no more than Kellgren-Lawrence grade II osteoarthrtis
3. No clinical suspicion of meniscus tear
4. Painless flexion-extension movements at knee joint.

Group Type ACTIVE_COMPARATOR

Will undergo a single MRI assessment with intravenous dye

Intervention Type OTHER

Group Four, any age due to undergo a surgical meniscus repair

1\. Patients should have presented with clinical signs to suggest meniscus tear indicating potential need for surgical meniscus repair

Group Type ACTIVE_COMPARATOR

pre and post surgery MRI scan

Intervention Type OTHER

Interventions

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Will undergo a single MRI assessment with intravenous dye

Intervention Type OTHER

pre and post surgery MRI scan

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Patients should be aged 18-20 years or 35-45years
2. Asymptomatic knee for past 6 months.
3. Painless flexion-extension movements at knee joint.

1. Patients should be aged 75 or older
2. Knee X-ray showing no more than Kellgren-Lawrence grade II osteoarthrtis
3. No clinical suspicion of meniscus tear
4. Painless flexion-extension movements at knee joint.

1\. Patients should have presented with clinical signs to suggest meniscus tear indicating potential need for surgical meniscus repair.

Exclusion Criteria

1. Proven Polyarthritis / Polyarthralgia secondary to Rheumatoid arthritis, Gout, Lupus, Ankylosing Spondylosis, Psoriatic arthritis
2. Any previous surgical procedure(open or arthroscopic) involving the knee joint.(baring the current meniscus repair in Group IV participants)
3. Patients unable to give informed consent.
4. Patients with contraindication for MR Imaging - Metal implants, prosthetic heart valves, pacemakers, metal foreign bodies, VP shunts, pregnancy, cochlear implant, metal clips in the brain, Patients with static tremor i.e. Parkinson's disease.
5. Patients with contraindications for contrast agent - Renal impairment, Previous allergic reaction.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No