WEakness and Atrophy: isoKinetic With Surface Electromyography Assessment in ACL Surgery

NCT ID: NCT03200678

Last Updated: 2022-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-05-07

Study Completion Date

2023-09-30

Brief Summary

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An assessment of the effect of surgical anterior cruciate ligament (ACL) on thigh muscles is critical to the improvement of knee rehabilitation and preservation. However, if a large number of studies had rated surgical technics, giving high results level for ACL reconstruction (ACLR), muscle recovery is still conditioning functional success. Furthermore there is no consensus about criteria in return to sport.

The aim of this exploratory study is to quantify the mechanisms of neuromuscular adaptation of muscle thigh after ACL surgery.

Detailed Description

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The aim of this study is to assess the qualitative and quantitative variations of the strength, work and fatigue of the thigh muscles after ACL surgery. The reference is the preoperative assessment (V1), the variation is measured on V2 (measurements at 3 months) and V3 (measures at 9 months). Each patient is his own control. In addition, a control group of healthy subjects is used to determine level of significance of each parameter.

Conditions

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Anterior Cruciate Ligament Injury Muscle Weakness

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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ACLR Group

experimental: ACL surgery Intervention: isokinetic assessment

Group Type EXPERIMENTAL

isokinetic assessment

Intervention Type OTHER

muscle torque assessement

Control group

other Intervention: isokinetic assessment

Group Type OTHER

isokinetic assessment

Intervention Type OTHER

muscle torque assessement

Interventions

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isokinetic assessment

muscle torque assessement

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

ACLR group :

* men or woman
* 18 to 45 years old
* No injuries sequels on contralateral limb
* No contraindication to magnetic resonance imaging

Control group :

* men or woman
* 18 to 45 years old
* No limb injuries sequels
* No contraindication to magnetic resonance imaging

Exclusion Criteria

* age less than 18 years
* limb injuries sequels
* contraindication to magnetic resonance imaging
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Direction Centrale du Service de Santé des Armées

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dominique Tardy

Role: PRINCIPAL_INVESTIGATOR

Direction Centrale du Service de Santé des Armées

Locations

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Hôpital d'Instruction des Armées Clermont-Tonnerre

Brest, , France

Site Status

Countries

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France

References

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Grimandi R, Tissier F, Garetier M, Labban J, Gerard R, Courtois-Communier E, Andro C, Bisseriex H, Gunepin FX, Rannou F, Giroux-Metges MA. Validity of the Uninjured Limb as a Control for Preoperative Assessment in Anterior Cruciate Ligament Reconstruction. J Orthop Res. 2025 May;43(5):962-972. doi: 10.1002/jor.26057. Epub 2025 Feb 21.

Reference Type DERIVED
PMID: 39981758 (View on PubMed)

Other Identifiers

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2017RC01

Identifier Type: OTHER

Identifier Source: secondary_id

2017-A00301-52

Identifier Type: -

Identifier Source: org_study_id

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