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Registry for Treatment of Upper Urinary Tract Tumours

NCT ID: NCT02281188

Last Updated: 2020-12-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2451 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-11-30

Study Completion Date

2024-03-31

Brief Summary

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The aim of this registry is to evaluate the incidence, indications and outcomes of patients presenting with UTUC in relation to the different treatment modalities used.

Detailed Description

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This is an observational international multi-center study in which data on consecutive patients with UUT tumours are collected. Centers from every continent may apply for participation in this registry. Data will be collected from consecutive patients over a five year period. Patients' data at baseline visit, at one year, three years and five years after inclusion in the registry will be recorded, as well as data on intra- and postoperative complications, recurrence and survival in the whole study period. Data from all participating centers will be collected through electronic case report forms (eCRFs), with use of an online Data Management System (DMS), which is located and maintained at the CROES Office.

Conditions

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Upper Urinary Tract Tumours

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Is presenting with a suspected primary UTUC (any stage)
* Is scheduled for treatment of UUT tumour
* Has signed informed consent
Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Clinical Research Office of the Endourological Society

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean de la Rosette

Role: STUDY_CHAIR

Clinical Research Office of the Endourological Society

Locations

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Amsterdam UMC

Amsterdam, , Netherlands

Site Status

Countries

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Netherlands

References

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Zhao H, Liu K, Crisci A, Te Slaa E, Habuchi T, Akand M, Ng CF, Laguna P, Teoh JY, de la Rosette J. Impact of smoking status at diagnosis on oncological outcomes of upper-tract urothelial carcinoma. Ther Adv Urol. 2025 Jun 28;17:17562872251352049. doi: 10.1177/17562872251352049. eCollection 2025 Jan-Dec.

Reference Type DERIVED
PMID: 40584958 (View on PubMed)

Liu K, Leung DK, Wong CH, Ko IC, Horuz R, Gontero P, Laguna P, de la Rosette J, Teoh JY. Influence of tumour location on the survival outcomes of upper tract urothelial carcinoma treated with radical nephroureterectomy. World J Urol. 2025 May 3;43(1):261. doi: 10.1007/s00345-024-05432-0.

Reference Type DERIVED
PMID: 40317391 (View on PubMed)

Liu K, Wong CH, Zhao H, Ng CF, Teoh JY, Laguna P, de la Rosette J. Impact of Antiaggregant and Anticoagulant Medications on Perioperative Complications in Upper Tract Urothelial Carcinoma. Eur Urol Open Sci. 2025 Mar 20;75:1-6. doi: 10.1016/j.euros.2025.02.007. eCollection 2025 May.

Reference Type DERIVED
PMID: 40206439 (View on PubMed)

Baard J, Cormio L, Dasgupta R, Maruzzi D, Rais-Bahrami S, Serrano A, Geavlete B, Giannakopoulos S, de la Rosette J, Laguna P. Unveiling the challenges of UTUC biopsies and cytology: insights from a global real-world practice study. World J Urol. 2024 Mar 20;42(1):177. doi: 10.1007/s00345-024-04866-w.

Reference Type DERIVED
PMID: 38507109 (View on PubMed)

Baard J, Shariat SF, Roupret M, Yoshida T, Saita A, Saltirov I, Burgos JR, Celik O, de la Rosette J, Laguna P. Adherence to guideline recommendations in the management of upper tract urothelial carcinoma: an analysis of the CROES-UTUC registry. World J Urol. 2022 Nov;40(11):2755-2763. doi: 10.1007/s00345-022-04168-z. Epub 2022 Oct 5.

Reference Type DERIVED
PMID: 36197507 (View on PubMed)

Baard J, Cormio L, Cavadas V, Alcaraz A, Shariat SF, de la Rosette J, Laguna MP. Contemporary patterns of presentation, diagnostics and management of upper tract urothelial cancer in 101 centres: the Clinical Research Office of the Endourological Society Global upper tract urothelial carcinoma registry. Curr Opin Urol. 2021 Jul 1;31(4):354-362. doi: 10.1097/MOU.0000000000000899.

Reference Type DERIVED
PMID: 34009177 (View on PubMed)

Baard J, Celebi M, de la Rosette J, Alcaraz A, Shariat S, Cormio L, Cavadas V, Laguna MP. Evaluation of Patterns of Presentation, Practice, and Outcomes of Upper Tract Urothelial Cancer: Protocol for an Observational, International, Multicenter, Cohort Study by the Clinical Research Office of the Endourology Society. JMIR Res Protoc. 2020 Jan 24;9(1):e15363. doi: 10.2196/15363.

Reference Type DERIVED
PMID: 32012106 (View on PubMed)

Related Links

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http://www.croesoffice.org

Related Info

Other Identifiers

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Registry UTUC

Identifier Type: -

Identifier Source: org_study_id