Histopathological Findings in En-Bloc vs Conventional Transurethral Resection of Bladder Tumors.
NCT ID: NCT07259798
Last Updated: 2025-12-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2024-08-01
2025-06-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
SINGLE
Study Groups
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Group A: Underwent En bloc Bipolar TURBT
En bloc TURBT using a bipolar Karl-Storz resectoscope system fitted with a specialized "flat" resection loop
A specialized "flat" resection loop (Karl-Storz En-Bloc Electrode, stainless steel, approximately 24 mm diameter). This loop features a broad, planar configuration with a smooth leading edge designed to dissect beneath the tumor base in a single piece while maintaining an intact specimen-muscle interface and minimizing fragmentation.
Group B: Bipolar piecemeal TURBT
Bipolar piecemeal TURBT using the same bipolar Karl-Storz resectoscopic platform
The resections were performed with a standard U-shaped cutting loop electrode (Karl-Storz, stainless steel, 24 mm diameter) mounted on a bipolar working element compatible with a 26-Fr continuous-flow resectoscope sheath and a 30-degree Hopkins® rod-lens telescope. The U-shaped loop, characterized by its semi elliptical contour and dual active cutting arms, facilitates sequential layer-by-layer resection of the tumor in multiple fragments, permitting simultaneous coagulation of bleeding vessels.
Interventions
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En bloc TURBT using a bipolar Karl-Storz resectoscope system fitted with a specialized "flat" resection loop
A specialized "flat" resection loop (Karl-Storz En-Bloc Electrode, stainless steel, approximately 24 mm diameter). This loop features a broad, planar configuration with a smooth leading edge designed to dissect beneath the tumor base in a single piece while maintaining an intact specimen-muscle interface and minimizing fragmentation.
Bipolar piecemeal TURBT using the same bipolar Karl-Storz resectoscopic platform
The resections were performed with a standard U-shaped cutting loop electrode (Karl-Storz, stainless steel, 24 mm diameter) mounted on a bipolar working element compatible with a 26-Fr continuous-flow resectoscope sheath and a 30-degree Hopkins® rod-lens telescope. The U-shaped loop, characterized by its semi elliptical contour and dual active cutting arms, facilitates sequential layer-by-layer resection of the tumor in multiple fragments, permitting simultaneous coagulation of bleeding vessels.
Eligibility Criteria
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Inclusion Criteria
* Patients fit for spinal or general anesthesia
Exclusion Criteria
* concomitant urothelial cancer of the upper urinary tract
* metastatic bladder cancer
18 Years
ALL
No
Sponsors
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Ain Shams University
OTHER
Responsible Party
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Younan Ramsis
Lecturer of Urology
Principal Investigators
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Mohammed K Ahmed, Assisstant Professor
Role: STUDY_DIRECTOR
Ain Shams University
Locations
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Ain Shams University
Cairo, Abbasia, Egypt
Countries
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References
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Yang H, Lin J, Gao P, He Z, Kuang X, Li X, Fu H, Du D. Is the En Bloc Transurethral Resection More Effective than Conventional Transurethral Resection for Non-Muscle-Invasive Bladder Cancer? A Systematic Review and Meta-Analysis. Urol Int. 2020;104(5-6):402-409. doi: 10.1159/000503734. Epub 2020 Jan 7.
Sun S, Wang H, Zhang X, Chen G. Transurethral Resection of Bladder Tumor: Novel Techniques in a New Era. Bladder (San Franc). 2023 Nov 9;10:e21200009. doi: 10.14440/bladder.2023.865. eCollection 2023.
Other Identifiers
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FMASU MS429/2024
Identifier Type: -
Identifier Source: org_study_id
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