Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early Diagnosis

NCT ID: NCT02280343

Last Updated: 2015-07-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-03-31

Study Completion Date

2016-03-31

Brief Summary

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Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and inertial properties. We believe that this technique may contribute to the early diagnosis of asbestosis.

Detailed Description

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The aims of this study were (1) to use the FOT to analyze how respiratory mechanics is affected in patients with asbestos exposed, (2) to identify the best FOT parameters for the diagnosis of respiratory changes in these patients (3) Assess whether the presence of obstructive changes is associated with the smoking habit.The control group (CG) included 24 subjects with normal spirometric data and without a history of smoking or pulmonary disease formed by workers and students UERJ and FioCruz. Volunteers with asbestos exposure were from the Department of CESTEH/ FioCruz, totaling 24 exposed and 7 with diagnoses of asbestosis.

The diagnosis of asbestosis was established based on a history of substantial exposure to asbestos dusts and compatible radiological features, together with exclusion of other competing diagnoses.

The tests included a standardized questionnaire on respiratory symptoms, clinical evaluation; Plain radiography of the chest; FOT, plethysmography and spirometry, in that order.

Conditions

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Asbestosis

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Interventions

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evaluated lung function

lung function tests

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* diagnosis of asbestosis

Exclusion Criteria

* other diseases
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Rio de Janeiro State University

OTHER

Sponsor Role lead

Responsible Party

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Paula Morisco de Sá

OSCILLATION MECHANICS OF THE RESPIRATORY SYSTEM ASBESTOS EXPOSED : Early diagnosis

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Paula Sá, research

Role: PRINCIPAL_INVESTIGATOR

Universidade do Estado do Rio de Janeiro:Brazil

Locations

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Paula Morisco de Sá

Rio de Janeiro, Rio de Janeiro, Brazil

Site Status RECRUITING

Countries

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Brazil

Central Contacts

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Paula Sá, research

Role: CONTACT

552123340705

Facility Contacts

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Paula M de Sá, researcher

Role: primary

552123340705

Other Identifiers

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UERJ

Identifier Type: -

Identifier Source: org_study_id

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