Longitudinal Clinical Evaluation of the HPV Assay on the BD VIPER LT System With Cervical Specimens

NCT ID: NCT02267876

Last Updated: 2021-02-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

6730 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-10-31

Study Completion Date

2019-05-31

Brief Summary

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The purpose of the study is to assess the cumulative disease detection of greater than or equal to Cervical intraepithelial neoplasia 2 (CIN2) and greater than or equal to Cervical intraepithelial neoplasia 3 (CIN3) in the subjects over 3 years using the subject's HPV status and cytology status from the BDS-USHPV baseline results

Detailed Description

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Conditions

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Cervical Neoplasms Human Papillomavirus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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BD VIPER LT

BD HPV Assay on Viper LT

Intervention Type DEVICE

The BD HPV specimen will be tested with the BD HPV Assay on the Viper LT instrument.

Colposcopy

Intervention Type PROCEDURE

The colposcopy will be performed on subjects that have abnormal cytology. At the third year visit all subjects will have an exit colposcopy.

Interventions

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BD HPV Assay on Viper LT

The BD HPV specimen will be tested with the BD HPV Assay on the Viper LT instrument.

Intervention Type DEVICE

Colposcopy

The colposcopy will be performed on subjects that have abnormal cytology. At the third year visit all subjects will have an exit colposcopy.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Subject enrolled into the protocol BDS-USHPV and identified as eligible for the longitudinal protocol • Subjects enrolled into protocol BDS-USHPV with a baseline colposcopy and biopsy procedure and not treated.

Exclusion Criteria

* Subjects with prior complete or partial hysterectomy involving removal of the cervix
* Subjects on whom conization, LEEP, cervical laser surgery, or cryosurgery has been performed since enrollment into the BDS-USHPV study
* Year 3 visit can not exceed 3 years and 6 months from the baseline visit
Minimum Eligible Age

21 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Becton, Dickinson and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tobi Karchmer, MD

Role: STUDY_DIRECTOR

Becton, Dickinson and Company

Locations

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University of Alabama

Birmingham, Alabama, United States

Site Status

Mobile OB/GYN

Mobile, Alabama, United States

Site Status

Women's Health Research of Arizona

Phoenix, Arizona, United States

Site Status

Quality of Life Medical & Research Center

Tucson, Arizona, United States

Site Status

Visions Clinical Research

Tucson, Arizona, United States

Site Status

Women's Health Care Research Corp.

San Diego, California, United States

Site Status

Blueskies Center for Women

Colorado Springs, Colorado, United States

Site Status

Health Awareness Inc.

Jupiter, Florida, United States

Site Status

Altus Research

Lake Worth, Florida, United States

Site Status

Segal Institute for Clinical Research

North Miami, Florida, United States

Site Status

Miami Research Associates

South Miami, Florida, United States

Site Status

Comprehensive Clinical Trails, LLC

West Palm Beach, Florida, United States

Site Status

Medical Network for Education & Research

Decatur, Georgia, United States

Site Status

Fellows Research Alliance - Savannah

Savannah, Georgia, United States

Site Status

Women's Health Practice

Champaign, Illinois, United States

Site Status

Indiana University

Indianapolis, Indiana, United States

Site Status

Four Rivers Clinical Research

Paducah, Kentucky, United States

Site Status

Louisiana State University

New Orleans, Louisiana, United States

Site Status

BD 54 Loveton

Sparks, Maryland, United States

Site Status

Saginaw Valley Medical Research

Saginaw, Michigan, United States

Site Status

Virtua Phoenix OB/GYN

Moorestown, New Jersey, United States

Site Status

Meridian Health / Jersey Shore University Medical Center

Neptune City, New Jersey, United States

Site Status

Quest Laboratories

Teterboro, New Jersey, United States

Site Status

TriCore

Albuquerque, New Mexico, United States

Site Status

Research Pathology Associates, LLC

Irvington, New York, United States

Site Status

Montefiore Medical Center

The Bronx, New York, United States

Site Status

Eastern Carolina Women's Center

New Bern, North Carolina, United States

Site Status

Lyndhurst Clinical Research

Winston-Salem, North Carolina, United States

Site Status

HWC Women's Research Center

Englewood, Ohio, United States

Site Status

Center for Women's Health of Lansdale

Lansdale, Pennsylvania, United States

Site Status

Clinical Research of Philadelphia

Philadelphia, Pennsylvania, United States

Site Status

Reading Health Physician Network

West Reading, Pennsylvania, United States

Site Status

Fellows Research Alliance - Bluffton

Bluffton, South Carolina, United States

Site Status

James T. Martin Jr. OB/GYN

North Charleston, South Carolina, United States

Site Status

Chattanooga Medical Research

Chattanooga, Tennessee, United States

Site Status

Center for Disease Detection, LLC

San Antonio, Texas, United States

Site Status

Physicians Research Options

Draper, Utah, United States

Site Status

Research Pathology Associates

Charlottesville, Virginia, United States

Site Status

Tidewater Clinical Research

Virginia Beach, Virginia, United States

Site Status

BioVision

Montreal, Quebec, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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BDS-USLHPV

Identifier Type: -

Identifier Source: org_study_id

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