Exercise and QUality Diet After Leukemia: The EQUAL Study
NCT ID: NCT02244411
Last Updated: 2025-07-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
358 participants
INTERVENTIONAL
2014-09-30
2025-07-16
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Intervention group
Participants will be assigned an individual diet \& physical activity counselor through Healthways at Hopkins. This counselor will stay with the participant for the 24 months. The primary communication with the counselor will be via website \& email. Participants will be encouraged to consume a low-calorie, low-salt diet with 7-12 daily servings of fruits, vegetables \& low-fat dairy products. Calorie goals are based upon weight at study entry \& whether or not the weight loss goal has been met. Participants will gradually build to ≥ 180 minutes of moderate to vigorous physical activity per week, using the activity of their own choosing \& gradually adding bouts of ≥ 10 minutes in length. Monitoring \& Counselor Contacts: the first 3 months, the participants are encouraged to log into the web hub on a daily basis to record weight, food intake, \& physical activity. Participants who decline or drop out of the intervention program will remain on-study doing home visits \& questionnaires.
individual diet & physical activity counselor and website through Healthways at Hopkins
Phone and web-based weight loss intervention (via Healthways at Hopkins counselor and website) focused on increasing physical activity and adhering to a healthy diet. Participants will log diet, physical activity, and weight in web-hub. Counselors will have access to this information to direct participants to goals and achievements.
questionnaires
Participants will complete behavioral questionnaires as well as diet and physical activity assessments through CCSS-based study website as baseline, 12 and 24 months.
fasting blood draw, measurement of height, weight and waist circumference, and blood pressure
During three time periods, at baseline and at 12 and 24 months.
control group
Participants will receive general information brochures on healthy living and weight loss but will not have access to the Healthways at Hopkins website or counselors.
self directed weight loss
Participants will be given information and links to CDC and American Cancer Society recommendations for healthy eating and physical activity.
questionnaires
Participants will complete behavioral questionnaires as well as diet and physical activity assessments through CCSS-based study website as baseline, 12 and 24 months.
fasting blood draw, measurement of height, weight and waist circumference, and blood pressure
During three time periods, at baseline and at 12 and 24 months.
Interventions
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individual diet & physical activity counselor and website through Healthways at Hopkins
Phone and web-based weight loss intervention (via Healthways at Hopkins counselor and website) focused on increasing physical activity and adhering to a healthy diet. Participants will log diet, physical activity, and weight in web-hub. Counselors will have access to this information to direct participants to goals and achievements.
self directed weight loss
Participants will be given information and links to CDC and American Cancer Society recommendations for healthy eating and physical activity.
questionnaires
Participants will complete behavioral questionnaires as well as diet and physical activity assessments through CCSS-based study website as baseline, 12 and 24 months.
fasting blood draw, measurement of height, weight and waist circumference, and blood pressure
During three time periods, at baseline and at 12 and 24 months.
Eligibility Criteria
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Inclusion Criteria
* Participation in the CCSS cohort
* Diagnosed with acute lymphoblastic leukemia \< 18 years of age
* Cancer free at time of study enrollment
* Current age ≥ 18 years
* A body mass index (BMI) ≥ 25 kg/m2 (overweight or obese), as determined by self-reported height and weight on the most recent CCSS questionnaire
* Internet access and a personal email account
* Able to read and comprehend informed consent
Exclusion Criteria
* Medical condition for which weight loss might be contraindicated or which would cause weight loss, such as pregnancy, anorexia or bulimia;
* Use of prescription weight loss medication within the previous 6 months
* History of total body irradiation (TBI)
18 Years
ALL
No
Sponsors
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Johns Hopkins University
OTHER
St. Jude Children's Research Hospital
OTHER
Memorial Sloan Kettering Cancer Center
OTHER
Responsible Party
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Principal Investigators
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Chaya Moskowitz, PhD
Role: PRINCIPAL_INVESTIGATOR
Memorial Sloan Kettering Cancer Center
Locations
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Memorial Sloan Kettering Cancer Center
New York, New York, United States
St. Jude Children's Research Hospital
Memphis, Tennessee, United States
Countries
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Related Links
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Memorial Sloan Kettering Cancer Center
Other Identifiers
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14-164
Identifier Type: -
Identifier Source: org_study_id
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