Effects of Fruit Juices on Hormone Metabolism

NCT ID: NCT02187328

Last Updated: 2014-07-11

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 12 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2014-06-30
• Study Completion Date: 2015-12-31

Brief Summary

The purpose of this study is to determine whether grapefruit juice alters the metabolism of cortisol following intense exercise.

Conditions

Cortisol

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Grapefruit juice

12.5 OZ Grapefruit juice: Subject will ingest grapefruit juice 12.5 OZ twice on the day of their scheduled laboratory visit. Once in the morning and once in the afternoon prior to their evening visit

Group Type: EXPERIMENTAL

Grapefruit juice

Intervention Type: OTHER

Volunteers participate in two visits at least 5 days apart. The day of their visit they ingest 12.5 oz of grapefruit juice in the morning and 12.5 oz of grapefruit juice ingested in the afternoon, 3h before reporting to the laboratory. The order of the visits is randomized, one visit volunteers ingest apple juice only, the other visit grapefruit juice only

Apple juice

10.5 OZ Apple juice: Subject will ingest apple juice 10.5 OZ twice on the day of their scheduled laboratory visit. Once in the morning and once in the afternoon 3 hours prior to their evening visit.

Group Type: PLACEBO_COMPARATOR

Apple juice

Intervention Type: OTHER

Volunteers participate in two visits at least 5 days apart. The day of their visit they ingest 12.5 oz of grapefruit juice or Apple juice ingested in the morning and 12.5 oz of grapefruit juice ingested in the afternoon, 3h before reporting to the laboratory. The order of the visits is randomized, one visit volunteers ingest apple juice only, the other visit grapefruit juice only

Interventions

Grapefruit juice

Volunteers participate in two visits at least 5 days apart. The day of their visit they ingest 12.5 oz of grapefruit juice in the morning and 12.5 oz of grapefruit juice ingested in the afternoon, 3h before reporting to the laboratory. The order of the visits is randomized, one visit volunteers ingest apple juice only, the other visit grapefruit juice only

Intervention Type: OTHER

Apple juice

Volunteers participate in two visits at least 5 days apart. The day of their visit they ingest 12.5 oz of grapefruit juice or Apple juice ingested in the morning and 12.5 oz of grapefruit juice ingested in the afternoon, 3h before reporting to the laboratory. The order of the visits is randomized, one visit volunteers ingest apple juice only, the other visit grapefruit juice only

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Young men and women, not taking medications known to alter glucocorticoid metabolism

Exclusion Criteria

• Diabetes, uncontrolled hypertension, obesity, any medication known to interact with grapefruit juice

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Benedictine University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Pedro Del Corral, PhD-MD

Role: PRINCIPAL_INVESTIGATOR

Benedictine University

Locations

Benedictine University

Lisle, Illinois, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Pedro Del Corral, PhD/MD

Role: CONTACT

pdelcorral@ben.edu

630 8296575

Facility Contacts

Meagan P Daniels

Role: primary

madaniel@ben.edu

Other Identifiers

Ben-0614a

Identifier Type: -

Identifier Source: org_study_id