A Grapefruit Feeding Trial in Healthy, Overweight Adults
NCT ID: NCT01452841
Last Updated: 2011-10-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
85 participants
INTERVENTIONAL
2009-08-31
2011-04-30
Brief Summary
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1. Reducing weight
2. Reducing blood pressure
3. Reducing inflammation
4. Improving the lipid profile.
The investigators hypothesize that six weeks of daily consumption of grapefruit will reduce weight, blood pressure, and inflammation while improving the lipid profile in overweight, healthy adults.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
PREVENTION
NONE
Study Groups
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Grapefruit Consumption
Grapefruit
1.5 Rio Red Grapefruit consumed daily for 6 weeks
Control
Control
Participants followed a diet low in bioactive rich fruits and vegetables and avoided citrus for six weeks
Interventions
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Grapefruit
1.5 Rio Red Grapefruit consumed daily for 6 weeks
Control
Participants followed a diet low in bioactive rich fruits and vegetables and avoided citrus for six weeks
Eligibility Criteria
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Inclusion Criteria
* BMI: 25-45 kg/m2
* Willing to maintain current exercise regimen (not to exceed 10 hours/week)
* Willing to follow a diet low in bioactive rich fruits and vegetables and with no citrus
Exclusion Criteria
* Metabolic disease
* Inflammatory disease
* High cholesterol (\>225 mg/dL)
* Smoker
* Taking medications metabolized by the Cytochrome P450 3A enzyme
* History of alcohol or drug abuse
18 Years
ALL
Yes
Sponsors
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Texas A&M University
OTHER
University of Arizona
OTHER
Responsible Party
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Principal Investigators
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Cynthia Thomson, PhD, RD
Role: PRINCIPAL_INVESTIGATOR
University of Arizona
Locations
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University of Arizona
Tucson, Arizona, United States
Countries
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Other Identifiers
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09-0695-02
Identifier Type: -
Identifier Source: org_study_id