The Influence of Adhesive Wafer Design on Fit to the Body

NCT ID: NCT02176954

Last Updated: 2015-03-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-07-31

Study Completion Date

2015-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of this study is to investigate the influence of the adhesive wafer design on the products ability to fit to the body..

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Ostomy - Ileostomy or Colostomy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Test A, Test B, Comparator

The subjects first test Coloplast Test A followed by Coloplast Test B and finally Comparator.

Group Type EXPERIMENTAL

Test A

Intervention Type DEVICE

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Test B

Intervention Type DEVICE

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Comparator

Intervention Type DEVICE

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Test A, Comparator, Test B

The subjects first test Coloplast Test A followed by Comparator and finally Coloplast Test B.

Group Type EXPERIMENTAL

Test A

Intervention Type DEVICE

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Test B

Intervention Type DEVICE

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Comparator

Intervention Type DEVICE

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Test B, Test A, Comparator

The subjects first test Coloplast Test B followed by Coloplast Test A and finally Comparator.

Group Type EXPERIMENTAL

Test A

Intervention Type DEVICE

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Test B

Intervention Type DEVICE

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Comparator

Intervention Type DEVICE

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Test B, Comparator, Test A

The subjects first test Coloplast Test B followed by Comparator and finally Coloplast Test B.

Group Type EXPERIMENTAL

Test A

Intervention Type DEVICE

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Test B

Intervention Type DEVICE

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Comparator

Intervention Type DEVICE

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Comparator, Test A, Test B

The subjects first test Comparator followed by Coloplast Test A and then Coloplast Test B

Group Type EXPERIMENTAL

Test A

Intervention Type DEVICE

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Test B

Intervention Type DEVICE

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Comparator

Intervention Type DEVICE

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Comparator, Test B, Test A

The subjects first test Comparator followed by Coloplast Test B and then Coloplast Test A.

Group Type EXPERIMENTAL

Test A

Intervention Type DEVICE

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Test B

Intervention Type DEVICE

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Comparator

Intervention Type DEVICE

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Test A

Test A is a new 1-piece ostomy appliance developed by Coloplast A/S

Intervention Type DEVICE

Test B

Test B is a new 1-piece ostomy appliance developed by Coloplast A/S

Intervention Type DEVICE

Comparator

Two comparators will be used: Moderma Flex (Hollister) or Confidence Natural drainable (Salts).These product are commercially available.

Subjects will be randomized into one of twelwe arms. Data will be analyzed by pooling the two comparators, Moderma Flex and Confidence Natural, Drainable, why six arms are displayed.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

To participate in the study, it is mandatory that the subject fulfill all inclusions criteria:

* Have given written informed consent and signed letter of Authority
* Be at least 18 years of age and have full legal capacity
* Have had their ileostomy or colostomy for at least 3 months
* Have a stoma with a diameter between 15 and 43 mm
* Be able to handle the product themselves
* Be able to use a custom cut product
* Normally experience faeces under the adhesive wafer at least 3 times during 2 weeks
* Currently using a 1-piece flat product or a 1-piece soft convex product
* Be willing to test products with open bag size maxi
* Be willing to test Moderma Flex or Confidence® Natural, Drainable and the two test products A and B
* Be willing to use minimum 1 test product every second day, i.e. maximum 48 hours wear time per product
* Be suitable for participating in the investigation
* Be willing to take/have taken pictures of the stoma before, during and after application of product

Exclusion Criteria

Subjects complying with the following criteria must be excluded from participation in the clinical investigation:

* Are currently receiving or have within the past 2 months received radio-and/or chemotherapy
* Are currently receiving or have within the past month received topical steroid treatment in the peri-stomal skin area or systemic steroid (tablet/injection) treatment
* Are pregnant or breastfeeding
* Are participating in other interventional clinical investigations or have previously participated in this investigation
* Use irrigation during the investigation (flush the intestines with water)
* Are currently suffering from peri-stomal skin problems i.e. bleeding and/or broken skin (assessed by the study nurse)
* Have a loop stoma
* Have known hypersensitivity towards any of the test products
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Coloplast A/S

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Khalid Abd-Elaziz, MD

Role: PRINCIPAL_INVESTIGATOR

QPS Netherlands

Susanne Eyre, MD

Role: PRINCIPAL_INVESTIGATOR

Synexus North East, United Kingdom

Gillian Hopkins

Role: PRINCIPAL_INVESTIGATOR

Cheltenham General Hospital, United Kingdom

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

QPS Netherlands

Groningen, , Netherlands

Site Status

Synexus Thames Valley

Berkshire, , United Kingdom

Site Status

Synexus Midlands

Birmingham, , United Kingdom

Site Status

Synexus Wales

Cardiff, , United Kingdom

Site Status

Synexus Scotland

Glasgow, , United Kingdom

Site Status

Cheltenham General Hospital

Gloucestershire, , United Kingdom

Site Status

Synesxus Lancashire

Lancashire, , United Kingdom

Site Status

Synexus Merseyside

Liverpool, , United Kingdom

Site Status

Synexus Manchester

Manchester, , United Kingdom

Site Status

Synexus North East

Northumberland, , United Kingdom

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Netherlands United Kingdom

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CP247

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Early and Late Implant Failure
NCT04270396 COMPLETED
Connective Tissue Graft Versus Collagen Matrix
NCT04210596 ACTIVE_NOT_RECRUITING NA