Accuracy of CNAP PPV Under General Anaesthesia

NCT ID: NCT02166580

Last Updated: 2017-06-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

54 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2015-07-31

Brief Summary

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Noninvasive pulse pressure variation for the guidance of perioperative fluid therapy is compared with the gold standard of invasive measurements. Cardiac output is derived by the PICCO monitor.

Hypothesis: Noninvasive CNAP PPV predicts fluid responsiveness. A grey zone for the prediction of fluid responsiveness will be defined.

Detailed Description

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Accuracy of PPV measured by two devices,PICCO and CNAP, is compared with the manually calculated PPV from the arterial line waveform. Established tests like passive leg raising and end-expiratory occlusion are used for prediction of fluid responsiveness. Intraoperative events like volume challenge are monitored.

Conditions

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General Anaesthesia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* major surgery
* need for invasive arterial measurements

Exclusion Criteria

* age under 18
* cardiac dysrhythmia
* vascular pathology at punction site
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Schleswig-Holstein

OTHER

Sponsor Role lead

Responsible Party

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Dr. Jochen Renner

PD Dr. med. Jochen Renner

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jochen Renner, PD Dr.

Role: PRINCIPAL_INVESTIGATOR

University Hospital Schleswig-Holstein, Departement of Anaesthesia and Intensive Care Medicine

Robert Hanss, Prof. Dr.

Role: PRINCIPAL_INVESTIGATOR

University Hospital Schleswig-Holstein, Departement of Anaesthesia and Intensive Care Medicine

Locations

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University Hospital, Schleswig-Holstein. Departement of Anaesthesiology and Intensive Care Medicine

Kiel, , Germany

Site Status

Countries

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Germany

References

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Renner J, Gruenewald M, Hill M, Mangelsdorff L, Aselmann H, Ilies C, Steinfath M, Broch O. Non-invasive assessment of fluid responsiveness using CNAP technology is interchangeable with invasive arterial measurements during major open abdominal surgery. Br J Anaesth. 2017 Jan;118(1):58-67. doi: 10.1093/bja/aew399.

Reference Type DERIVED
PMID: 28039242 (View on PubMed)

Other Identifiers

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CNAP 2012_2

Identifier Type: -

Identifier Source: org_study_id

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