Comparing Weaning of Nasal Continuous Positive Airway Pressure (CPAP) From Preterm Infants

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-12-31

Study Completion Date

2015-12-31

Brief Summary

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To compare the 2 methods of weaning of nasal continuous positive airway pressure (CPAP) in premature babies born between 26 and 32 weeks

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Detailed Description

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To study the weight and the post menstrual age (PMA) at the time of NCPAP wean utilizing the method of sudden wean as compared to gradual wean.

Methods: A prospective randomized trial was conducted comparing sudden weaning with gradual weaning from NCPAP in neonates with gestational age between 26 and 32 weeks. The patients were randomized to one of the two methods of weaning from NCPAP and their success was compared

Conditions

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Respiratory Distress Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Sudden wean

When ready Nasal Continuous Positive Airway Pressure (NCPAP) will be removed from the neonate

Group Type NO_INTERVENTION

No interventions assigned to this group

Gradual pressure wean

NCPAP will be removed by gradually decreasing pressure over 24 hours once the weaning is decided

Group Type ACTIVE_COMPARATOR

Gradual pressure wean

Intervention Type OTHER

NCPAP will be removed by gradually decreasing pressure over 24 hours once the weaning is decided

Interventions

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Gradual pressure wean

NCPAP will be removed by gradually decreasing pressure over 24 hours once the weaning is decided

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All neonates born 26 to 32 weeks of gestational age

Exclusion Criteria

* Those with severe congenital anomalies and chromosomal defects including congenital heart disease, neurological malformations, chest and airway abnormalities and lung hypoplasia

Minimum Eligible Age

26 Weeks

Maximum Eligible Age

32 Weeks

Eligible Sex

ALL

Accepts Healthy Volunteers

No