Allocentric Memory in MS and Resting State Functional MRI
NCT ID: NCT02118298
Last Updated: 2016-05-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
120 participants
OBSERVATIONAL
2014-04-30
2016-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Multiple Sclerosis
Ages 18 - 66, 10 years or less of MS,
No interventions assigned to this group
Demographically matched controls
Ages 18 - 66, No known neurological disorder, no learning disorder, and no psychiatric disturbance that is actually interfering with life.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Right handed
* Capacity to provide informed consent and sign consent
* Diagnosis of Relapsing Remitting MS that meets the revised McDonald Criteria (2010) within the last 10 years
* EDSS 0- 5.5
Exclusion Criteria
* Contraindications for MRI
* Subjects required to take medications known to either benefit or adversely affect cognition at the time of testing and impact neuroimaging
* Non-MS neurological disorders
* Other medical or psychiatric disorders likely to affect cognitive performance
* Active immunodeficiency, chronic infections, or history or progressive multifocal leukoencephalopathy
* Individuals with severe level of depression on the BDI-II or severe anxiety on the BAI
* MS subjects who are actively experiencing acute exacerbation in symptoms and they must be at least 4 weeks free of steroid medication, are currently taking a chemotherapy agent, or have changed medication in the last two months
* Subjects who fail symptom validity measures during neuropsychological testing will be excluded
18 Years
55 Years
ALL
Yes
Sponsors
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Yale University
OTHER
Responsible Party
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Principal Investigators
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Franklin C Brown, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
Yale University
Locations
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Yale University
New Haven, Connecticut, United States
Countries
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Other Identifiers
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1401013272
Identifier Type: -
Identifier Source: org_study_id
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