Body Responses to Bean Physical Form and "Beano"

NCT ID: NCT02110511

Last Updated: 2014-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-08-31

Study Completion Date

2012-10-31

Brief Summary

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The aim of this study is to determine the effects of bean physical form (whole versus blended) and Beano on postprandial responses. The postprandial responses the investigators will examine include blood glucose, appetite, metabolic rate, physical symptoms, and mood. To accomplish this aim the investigators will conduct a randomized, placebo-controlled trial in overweight and obese but otherwise healthy (non-diabetic) men and women

Detailed Description

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Conditions

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Appetite and Glucose Responses

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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alpha-gal & blended lentils

3 capsules of alpha-gal taken with blended lentils

Group Type EXPERIMENTAL

blended lentils

Intervention Type OTHER

blended lentils burritto breakfast

alpha-gal & whole lentils

3 calpsules of alpha-gal taken with whole lentils

Group Type EXPERIMENTAL

whole lentils

Intervention Type OTHER

whole lentils breakfast burritto

alpha-gal & no lentils

3 capsules of alpha-gal taken with no lentils control

Group Type EXPERIMENTAL

no lentils

Intervention Type OTHER

No lentils control breakfast burritto

Placebo & blended lentils

3 capsules of placebo taken with blended lentils

Group Type PLACEBO_COMPARATOR

blended lentils

Intervention Type OTHER

blended lentils burritto breakfast

Placebo & whole lentils

3 capsules of placebo taken with whole lentils

Group Type PLACEBO_COMPARATOR

whole lentils

Intervention Type OTHER

whole lentils breakfast burritto

Placebo & no lentils

3 capsules of placebo taken with no lentils control

Group Type PLACEBO_COMPARATOR

no lentils

Intervention Type OTHER

No lentils control breakfast burritto

Interventions

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blended lentils

blended lentils burritto breakfast

Intervention Type OTHER

whole lentils

whole lentils breakfast burritto

Intervention Type OTHER

no lentils

No lentils control breakfast burritto

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Aged 18-55 years old
* Body mass index (BMI) 18.5-40 kg/m2
* Generally healthy
* A non-smoker
* Any ethnicity
* Free of chronic diseases and not taking medications or dietary supplements known to affect energy regulation or appetite

Exclusion Criteria

* Beano drug label warnings including galactosemia, severe liver or kidney disease, allergies or sensitivities to any of the ingredients in Beano
* Peri and postmenopausal women
* Pregnant or lactating women (currently and within the past 1 year)
* Currently dieting or consuming unusual or a medically prescribed diet
* Net weight loss or gain (\>5 lbs) within the last six months
* Consuming 1/2c per day or more of legumes, not including peanuts
* Having taken Beano any time in the past 3 months
* Extreme problems digesting beans
* Fasting glucose \>126 mg/dl
* Blood pressure \>140/90 mmHg
* Moderate intensity or higher intensity exercise \> 6 h/wk
* Predicted energy requirement \< 2000 kcal/d or \>4000 kcal/d
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Purdue University

OTHER

Sponsor Role lead

Responsible Party

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Megan McCrory

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Purdue University

West Lafayette, Indiana, United States

Site Status

Countries

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United States

References

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Anguah KO, Wonnell BS, Campbell WW, McCabe GP, McCrory MA. A blended- rather than whole-lentil meal with or without alpha-galactosidase mildly increases healthy adults' appetite but not their glycemic response. J Nutr. 2014 Dec;144(12):1963-9. doi: 10.3945/jn.114.195545. Epub 2014 Oct 8.

Reference Type DERIVED
PMID: 25411033 (View on PubMed)

Other Identifiers

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1107011010

Identifier Type: -

Identifier Source: org_study_id

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