Porphyromonas Gingivalis and Alzheimer's Disease

NCT ID: NCT02109705

Last Updated: 2023-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

90 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-03-31

Study Completion Date

2021-01-31

Brief Summary

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With this study the investigators would like to analyze the the role of periodontal disease and especially the role of Porphyromonas gingivalis in initiation and progression of Alzheimer's Disease.

Detailed Description

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Conditions

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Alzheimer's Disease Dementia Periodontitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Alzheimer's Disease

No interventions assigned to this group

other Dementia

No interventions assigned to this group

cognitive healthy

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age 40-70
* caucasian origin
* dementia (Alzheimer's or other dementia)
* cognitive healthy (need for spinal anesthesia)

Exclusion Criteria

* use of antibiotics within las 6 months
* pregnancy
* another illness explaining the symptoms in a better way
* smoking (\>10 cigarettes)
* patients who have a legal custodian
Minimum Eligible Age

40 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Bern

OTHER

Sponsor Role collaborator

University Hospital Muenster

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Oliver Laugisch, Dr med dent MAS

Role: PRINCIPAL_INVESTIGATOR

Department of Periodontology

Locations

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Department of Periodontology

Münster, , Germany

Site Status

Countries

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Germany

Other Identifiers

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PG001

Identifier Type: -

Identifier Source: org_study_id

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