Diagnostic Accuracy of Pleural Effusion Aspergillosis Biomarker Testing
NCT ID: NCT02104479
Last Updated: 2020-04-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
200 participants
OBSERVATIONAL
2014-03-31
2020-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Immunocompromised Patients
Immunocompromised patients with suspected IPA who have Pleural effusions act as the observed study population
No interventions assigned to this group
Control Group
Patients without Immunosuppression with pleural effusions
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* after allogeneic stem cell transplantation or solid organ transplantation,
* Patients wth acute leukemia in induction treatment,
* patients witrh graft-versus-host-disease,
* patients under chronic immunusuppressive therapy such as ciclosporin,
* patients with HIV,
* patients with chronic steroid treatment
Exclusion Criteria
* missing informed consent
* contraindication for pleural centesis
18 Years
ALL
No
Sponsors
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Pfizer
INDUSTRY
Heidelberg University
OTHER
Responsible Party
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Dieter Buchheidt
MD
Principal Investigators
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Dieter Buchheidt, MD
Role: PRINCIPAL_INVESTIGATOR
Universitätsmedizin Mannheim
Locations
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University Hospital Mannheim
Mannheim, Baden-Wuerrtemberg, Germany
Wuerzburg University Hospital
Würzburg, Bavaria, Germany
Countries
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References
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Reinwald M, Spiess B, Heinz WJ, Heussel CP, Bertz H, Cornely OA, Hahn J, Lehrnbecher T, Kiehl M, Laws HJ, Wolf HH, Schwerdtfeger R, Schultheis B, Burchardt A, Klein M, Durken M, Claus B, Schlegel F, Hummel M, Hofmann WK, Buchheidt D. Aspergillus PCR-based investigation of fresh tissue and effusion samples in patients with suspected invasive Aspergillosis enhances diagnostic capabilities. J Clin Microbiol. 2013 Dec;51(12):4178-85. doi: 10.1128/JCM.02387-13. Epub 2013 Oct 9.
Other Identifiers
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EFFU-ASP 2014
Identifier Type: -
Identifier Source: org_study_id
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