Randomized, Prospective Evaluation of the Toad Brace in Plantar Ulcer Off-loading and Healing

NCT ID: NCT02052817

Last Updated: 2014-02-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

74 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-12-31

Brief Summary

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The TOAD Medical Corporation Brace is a novel device that completely off-loads the foot and has been shown to heal ulcers at a rapid rate in preliminary experience in patients with plantar ulcers. This trial will attempt to show the efficacy of the Toad Brace and is based on the hypothesis that the Toad brace completely offloads the foot and hastens healing rates of diabetic ulcers. The trial will randomize 74 patients with diabetic pedal ulcers to the Toad Brace or conventional therapy. . Quantitative assessment of ulcer rate healing rates will be determined clinically and by blinded, computer-assisted planimetry of digital images over a 12 week period. The pressure on the plantar surface will be measured via a pressure sensor in a subset of patients. The trials will attempt to show markedly reduced pressure on the plantar surface and significantly higher ulcer healing rates with using the Toad Brace.

Detailed Description

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Conditions

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Diabetic Foot Pedal Ulcers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Control

Debridement and standard of care in off-loading on control patients

Group Type ACTIVE_COMPARATOR

Optimal Medical Therapy - Debridement

Intervention Type OTHER

Toad Brace

Debridement and fitting of Toad Brace

Group Type EXPERIMENTAL

Optimal Medical Therapy Debridement + Toad Brace

Intervention Type DEVICE

Interventions

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Optimal Medical Therapy Debridement + Toad Brace

Intervention Type DEVICE

Optimal Medical Therapy - Debridement

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Men or women \>18 years old
* One or more foot ulcers without clinical evidence of osteomyelitis
* Diagnosis of Diabetes Mellitus\*
* University of Texas Grade 1A, 1C, 2A, or 2C ulcer15
* ABI \>0.7 and Toe pressure \>30mmHg

Exclusion Criteria

* Limited life-expectancy
* Wounds on calf or shin that would be in contact with the TAG Brace
* Gangrene, active infection
* Osteomyelitis of the foot with the ulcer
* Chronically bedridden/Non ambulatory
* Unable to keep research appointments
* Wide spread malignancy or systemically immunocompromising disease
* Ipsilateral revascularization procedure within the last 30 days.
* Unreliable, unwilling or unable to comprehend informed consent
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospitals Cleveland Medical Center

OTHER

Sponsor Role collaborator

Toad Medical Corporation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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UH Hospitals of Cleveland d/b/a University Hospitals Case Medical

Cleveland, Ohio, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Lori Hammer, RN

Role: CONTACT

216-983-4719

Other Identifiers

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Toad_Brace_07-13-11

Identifier Type: -

Identifier Source: org_study_id

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