Women With Migraine With Aura Neuroimaging Study

NCT ID: NCT02047695

Last Updated: 2017-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

345 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-02-28

Study Completion Date

2017-04-30

Brief Summary

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The purpose of this study is to investigate whether a particular form of migraine, migraine with aura, is associated with structural changes in the brain

Detailed Description

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Conditions

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Migraine With Aura

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Migraine with aura

Participants with migraine with aura (cases), their co-twins, and unrelated migraine-free twins (controls)

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* female
* case (migraine with aura), co-twin to case, or control (migraine-free)
* residency in Denmark
* no severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders

Exclusion Criteria

* male
* residency outside Denmark
* registered in Civil Registry as not to be contacted by researchers
* severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders
* mobile metal parts or other contraindication for MRI
* weight of 130+ kilograms
* pregnancy
* subjects that wished not to be informed about abnormal findings on MRI
* chronic tension-type headache, medication overuse headache, or cluster headache (diagnosed through physician interview)
* frequent tension-type headache (control group only, self-reported or diagnosed through physician interview)
Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Glostrup University Hospital, Copenhagen

OTHER

Sponsor Role collaborator

Copenhagen University Hospital, Hvidovre

OTHER

Sponsor Role collaborator

University of Southern Denmark

OTHER

Sponsor Role collaborator

Odense University Hospital

OTHER

Sponsor Role lead

Responsible Party

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David Gaist

professor, consultant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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David Gaist, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Neurology, Odense University Hospital

Other Identifiers

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S-20100126

Identifier Type: -

Identifier Source: org_study_id

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