Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
550 participants
OBSERVATIONAL
2004-04-30
2020-03-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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twins
twin pairs
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
6 Years
ALL
Yes
Sponsors
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National Institute of Mental Health (NIMH)
NIH
University of North Carolina, Chapel Hill
OTHER
Responsible Party
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Principal Investigators
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John H Gilmore, MD
Role: PRINCIPAL_INVESTIGATOR
University of North Carolina, Chapel Hill
Locations
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UNC Department of Psychiatry
Chapel Hill, North Carolina, United States
Countries
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References
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Mukherjee N, Kang C, Wolfe HM, Hertzberg BS, Smith JK, Lin W, Gerig G, Hamer RM, Gilmore JH. Discordance of prenatal and neonatal brain development in twins. Early Hum Dev. 2009 Mar;85(3):171-5. doi: 10.1016/j.earlhumdev.2008.07.008. Epub 2008 Sep 19.
Gilmore JH, Schmitt JE, Knickmeyer RC, Smith JK, Lin W, Styner M, Gerig G, Neale MC. Genetic and environmental contributions to neonatal brain structure: A twin study. Hum Brain Mapp. 2010 Aug;31(8):1174-82. doi: 10.1002/hbm.20926.
Knickmeyer RC, Kang C, Woolson S, Smith JK, Hamer RM, Lin W, Gerig G, Styner M, Gilmore JH. Twin-singleton differences in neonatal brain structure. Twin Res Hum Genet. 2011 Jun;14(3):268-76. doi: 10.1375/twin.14.3.268.
Geng X, Prom-Wormley EC, Perez J, Kubarych T, Styner M, Lin W, Neale MC, Gilmore JH. White matter heritability using diffusion tensor imaging in neonatal brains. Twin Res Hum Genet. 2012 Jun;15(3):336-50. doi: 10.1017/thg.2012.14.
Li Y, Gilmore JH, Wang J, Styner M, Lin W, Zhu H. TwinMARM: two-stage multiscale adaptive regression methods for twin neuroimaging data. IEEE Trans Med Imaging. 2012 May;31(5):1100-12. doi: 10.1109/TMI.2012.2185830. Epub 2012 Jan 24.
Lee SJ, Steiner RJ, Luo S, Neale MC, Styner M, Zhu H, Gilmore JH. Quantitative tract-based white matter heritability in twin neonates. Neuroimage. 2015 May 1;111:123-35. doi: 10.1016/j.neuroimage.2015.02.021. Epub 2015 Feb 17.
Gao W, Elton A, Zhu H, Alcauter S, Smith JK, Gilmore JH, Lin W. Intersubject variability of and genetic effects on the brain's functional connectivity during infancy. J Neurosci. 2014 Aug 20;34(34):11288-96. doi: 10.1523/JNEUROSCI.5072-13.2014.
Jha SC, Xia K, Ahn M, Girault JB, Li G, Wang L, Shen D, Zou F, Zhu H, Styner M, Gilmore JH, Knickmeyer RC. Environmental Influences on Infant Cortical Thickness and Surface Area. Cereb Cortex. 2019 Mar 1;29(3):1139-1149. doi: 10.1093/cercor/bhy020.
Lee SJ, Zhang J, Neale MC, Styner M, Zhu H, Gilmore JH. Quantitative tract-based white matter heritability in 1- and 2-year-old twins. Hum Brain Mapp. 2019 Mar;40(4):1164-1173. doi: 10.1002/hbm.24436. Epub 2018 Oct 27.
Jha SC, Xia K, Schmitt JE, Ahn M, Girault JB, Murphy VA, Li G, Wang L, Shen D, Zou F, Zhu H, Styner M, Knickmeyer RC, Gilmore JH. Genetic influences on neonatal cortical thickness and surface area. Hum Brain Mapp. 2018 Dec;39(12):4998-5013. doi: 10.1002/hbm.24340. Epub 2018 Aug 24.
Other Identifiers
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03-0989
Identifier Type: -
Identifier Source: org_study_id
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