Observational Study of Choline, Its Metabolites, and Phospholipids in Preterm Infants
NCT ID: NCT02027584
Last Updated: 2014-01-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
414 participants
OBSERVATIONAL
2008-11-30
2013-07-31
Brief Summary
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Detailed Description
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To determine concentrations of choline, its metabolites, and phospholipids by mass spectrometry.
To compare cord plasma concentrations with postnatal plasma concentrations.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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parturient
mother who had given birth within 48 hours of clinically indicated blood sampling
collection of remnant of clinically indicated blood sample
collection of remnant of clinically indicated blood sample
healthy, non-pregnant, female volunteers
healthy, non-pregnant, female volunteers
collection of remnant of clinically indicated blood sample
collection of remnant of clinically indicated blood sample
preterm infant
gestational age at birth \< 37 weeks
collection of remnant of clinically indicated blood sample
collection of remnant of clinically indicated blood sample
term infant
gestational age at birth \>36 weeks
collection of remnant of clinically indicated blood sample
collection of remnant of clinically indicated blood sample
Interventions
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collection of remnant of clinically indicated blood sample
collection of remnant of clinically indicated blood sample
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
6 Months
ALL
Yes
Sponsors
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Universität Tübingen
OTHER
University Hospital Tuebingen
OTHER
Responsible Party
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Principal Investigators
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Wolfgang Bernhard, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University Hospital Tuebingen
Locations
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University Hospital Tuebingen
Tübingen, , Germany
Countries
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References
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Bernhard W, Full A, Arand J, Maas C, Poets CF, Franz AR. Choline supply of preterm infants: assessment of dietary intake and pathophysiological considerations. Eur J Nutr. 2013 Apr;52(3):1269-78. doi: 10.1007/s00394-012-0438-x. Epub 2012 Sep 9.
Bernhard W, Raith M, Kunze R, Koch V, Heni M, Maas C, Abele H, Poets CF, Franz AR. Choline concentrations are lower in postnatal plasma of preterm infants than in cord plasma. Eur J Nutr. 2015 Aug;54(5):733-41. doi: 10.1007/s00394-014-0751-7. Epub 2014 Aug 23.
Other Identifiers
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NEO-CHOLIN
Identifier Type: -
Identifier Source: org_study_id
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