Descriptive Study of Brain Velocity in Transcranial Doppler in Newborns Over 35 Weeks of Gestational Age in the Maternity Ward

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

41 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-04-19

Study Completion Date

2018-10-25

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

There are significant variations in blood circulation at birth with the transition from fetal to permanent circulation. These variations are particularly impacted by the closure of the arterial canal within the first 48 hours of life.

Blood circulation velocity values within the cerebral arteries have been well documented in newborns and infants a few days old. However, the initial values of these velocities and their variations during the first hours of life are not well known.

The objective of this study is to describe the evolution of brain circulation at birth in newborns over 35 weeks of gestational age and to investigate the effect of arterial canal closure on brain circulation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Sonographic QUantification of Venous Circulation In the Preterm Brain

NCT04535375

Prematurity; Extreme Cerebral Circulatory Failure Intraventricular Hemorrhage +1 more

COMPLETED NA

Study on the Development of Neonatal Cerebral Blood Flow Based on Ultrafast Ultrasound Doppler Imaging

NCT05761548

Premature Birth

UNKNOWN

Cerebral Blood Flow Parameters and Neurobehavioral Development in Infants at Term Age

NCT00676247

Premature Birth

COMPLETED

NeoDoppler: New Ultrasound Technology for Continuous Monitoring of Cerebral Circulation Pilot

NCT06646250

Preterm Patent Ductus Arteriosus Sepsis +4 more

RECRUITING

Neonate Cerebral Activity in Immediate Post Partum

NCT04225975

Anoxia-Ischemia, Brain Neonatal Encephalopathy

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Newborn

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

transcranial doppler ultrasound scan

Carried out at 4 different times: at birth, 6, 24 and 48 hours of life (duration: 10 minutes)

Intervention Type DIAGNOSTIC_TEST

ultrasound scan centered on the arterial canal

Carried out at 4 different times: at birth, 6, 24 and 48 hours of life (duration: 5 minutes)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Written consent of parent
* Newborns over 35 weeks of amenorrhoea hospitalized in the maternity ward

Exclusion Criteria

* person not affiliated to a health insurance scheme
* Sepsis
* Ductal dependent heart disease
* Neurological impairment (anoxoischemic encephalopathy Sarnat\>1, pH\<7 and/or lactates\>11, meningitis)
* Obstetrical trauma (instrumental delivery by forceps, vacuum cup or spatulas)
* Potentially lethal malformation
* Anemia (hemoglobin\<14g/dl)
* Polyglobulia (hemoglobin\>22g/dl)
* Small for gestational age (weight\<10th percentile)
* Large for gestational age (weight\>97th percentile)
* Proven gestational diabetes (non-insulin-dependent and insulin-dependent)
* Maternal medical treatment (cardiac or anti-epileptic)
* Inadequate parent understanding

Maximum Eligible Age

6 Hours

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes