Tryptophan Requirement of Healthy School Age Children

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

7 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-12-31

Study Completion Date

2017-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Our objective is to determine the requirement for the amino acid tryptophan in school age children using the indicator amino acid technique.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

MA of Tryptophan in Cornmeal in Healthy Adults>60y

NCT07272668

Protein Absorption and Amino Acid Availability

ENROLLING_BY_INVITATION NA

Metabolic Availability of Tryptophan From White Maize

NCT02402179

Healthy

COMPLETED NA

Determination of Threonine Requirements in Healthy School-aged Children

NCT02660892

Threonine Requirements in Children

COMPLETED NA

Glutathione (GSH) Synthesis in Healthy School-aged Children and Healthy Young and Old Adults

NCT02971046

Healthy

ACTIVE_NOT_RECRUITING NA

Assessment of the Optimal Amount of Proteins at Breakfast for Children

NCT02465151

Healthy Children

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Seven healthy children will participate in the study. The children will participate as an outpatient basis with study days carried out in the Physiological Research Unit at the Hospital of Sick Children, Toronto, Canada. Inclusion criteria include: being healthy, not taking any medications, no recent weight changes, no history of significant illness, willing to participate in the study. Exclusion criteria were the presence of illness, significant weight change, not acceptance of the diet. Prior to enrolment, each subject will have to fill 3 days food record form to ensure his or her normal dietary behavior. The study will be explained to subjects and their parents/guardians, benefits and potential risks will be explained as well and written assent, from the children, and consent from parents will be obtained. Subjects will receive financial compensations. Each subject will receive compensation for participation. Each parent/guardian will be reimbursed for the transpiration/parking expenses and a meal each study day.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Healthy

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

tryptophan intake

Graded levels of tryptophan will be given to each subject on different study days around the anticipated breakpoint.

Group Type EXPERIMENTAL

tryptophan

Intervention Type DIETARY_SUPPLEMENT

graded levels of tryptophan will be given to each subject

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

tryptophan

graded levels of tryptophan will be given to each subject

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Healthy children age 6-10 inclusive

Exclusion Criteria

* significant recent illness

Minimum Eligible Age

6 Years

Maximum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Dr. Paul Pencharz

Professor of Paediatrics and Nutritional Sciences (Emeritus) University of Toronto, Senior Scientist Research Institute, The Hospital for Sick Children

Responsibility Role PRINCIPAL_INVESTIGATOR