Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment

NCT ID: NCT01559766

Last Updated: 2012-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

403 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-07-31

Study Completion Date

2010-09-30

Brief Summary

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Vitamin A deficiency remains a major public health problem in developing country worldwide. Young Children are considered to be at greatest risk of deficiency. However, there is little information on the vitamin A requirement of Chinese children. In the present study, about 400 children aged between 4 and 9 years old in a kindergarten and an elementary school of Shiyan City were screened before admission by questionnaire and anthropometric measurement. The vitamin A status of children was assessed by serum vitamin A level, relative dosage reaction and stable-isotope dilution technique. At the same time, their dietary vitamin A intakes were estimated by weighted-food dietary survey. The dietary vitamin A requirement in young children was determined on the basis of dietary vitamin A intakes in Children with adequate vitamin A level.

Detailed Description

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Conditions

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Vitamin A Deficiency

Study Design

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Study Time Perspective

CROSS_SECTIONAL

Study Groups

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4-6 years old group

No interventions assigned to this group

7-9 years old group

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* well-nourished children with normal serum retinol(\>=1.40umol/L)

Exclusion Criteria

* ongoing or previous illnesses,
* having taken nutritional supplements within 3 months,
* positive results in the fat absorption test or parasite test,
* increased level of CRP (\> 8 mg/L), or
* lower serum level of retinol (\< 1.40 umol/L)
Minimum Eligible Age

4 Years

Maximum Eligible Age

9 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ShiYan Centre for Disease Control and Prevention

UNKNOWN

Sponsor Role collaborator

Tufts Medical Center

OTHER

Sponsor Role collaborator

Huazhong University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Xiufa Sun

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Xiufa Sun, BS

Role: PRINCIPAL_INVESTIGATOR

Tongji Medical College, Huazhong University of Science and Technology

Locations

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Shiyan Centre for Disease Control and Prevention

Shiyan, Hubei, China

Site Status

Countries

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China

Other Identifiers

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No.2008BAI58B03

Identifier Type: -

Identifier Source: org_study_id

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